Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …

Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …

Importance Sickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized
by formation of long chains of hemoglobin when deoxygenated within capillary beds …

Sickle cell disease (SCD) is an umbrella term for a group of life‐long debilitating autosomal
recessive disorders that are caused by a single‐point mutation (Glu→ Val) that results in …

Sickle cell disease (SCD) is a single gene disorder causing a debilitating systemic
syndrome characterised by chronic anaemia, acute painful episodes, organ infarction and …

Sickle cell disease is an umbrella term for a group of hemoglobinopathies characterized by
the presence of 2 β-globin gene mutations or deletions, at least 1 of which is the point …

Aims: To develop a strategy for neonatal screening of sickle cell disease (SCD) and effective
enrolment of affected neonates in a comprehensive follow-up programme adapted to the …

Sickle cell disease (SCD) is a chronic hemolytic anemia that includes the hemoglobin (Hb)
variants SS, SC, S-beta thalassemia, SO Arab, SD, and other rare S-Hb genotypes. SCD is …

Homozygous sickle cell disease (SCD) is an autosomal recessive genetic disease that
results from the substitution of valine for glutamic acid at position 6 of the β-globin gene …

Background: As a result of population growth in African-Caribbean regions of overseas
France, and now immigration essentially from North and sub-Saharan Africa to mainland …