Brain structural and functional alterations in native Tibetans living at high altitude

X Zhang, W Xie, Y Liu, M Li, J Lin, W Yin, L Yang, P Li… - Neuroscience, 2023 - Elsevier
Tibetans have adapted to high altitude environments. However, the genetic effects in their
brains have not been identified. Twenty-five native Tibetans living in Lhasa (3650 m) were …

Consistent differences in brain structure and functional connectivity in high-altitude native Tibetans and immigrants

X Zhang, W Xie, W Du, Y Liu, J Lin, W Yin… - Brain Imaging and …, 2023 - Springer
It has been well-established that high-altitude (HA) environments affect the human brain;
however, the differences in brain structural and functional networks between HA natives and …

Cortical thickness of native tibetans in the qinghai-tibetan plateau

W Wei, X Wang, Q Gong, M Fan… - American Journal of …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: High-altitude environmental factors and genetic variants
together could have exerted their effects on the human brain. The present study was …

Adaptive modulation of adult brain gray and white matter to high altitude: structural MRI studies

J Zhang, H Zhang, J Li, J Chen, Q Han, J Lin, T Yang… - PloS one, 2013 - journals.plos.org
The aim of this study was to investigate brain structural alterations in adult immigrants who
adapted to high altitude (HA). Voxel-based morphometry analysis of gray matter (GM) …

Reversible brain abnormalities in people without signs of mountain sickness during high-altitude exposure

C Fan, Y Zhao, Q Yu, W Yin, H Liu, J Lin, T Yang… - Scientific reports, 2016 - nature.com
A large proportion of lowlanders ascending to high-altitude (HA) show no signs of mountain
sickness. Whether their brains have indeed suffered from HA environment and the persistent …

Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude

X Li, H Ma, X Ding, H Jiang, X Zhang - Neuroscience, 2023 - Elsevier
Mental rotation is a core indicator of spatial ability, and a threshold for cognitive impairment
may exist at approximately 4,000 m above sea level, but the specific thresholds for the …

The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

Competition among the attentional networks due to resource reduction in Tibetan indigenous residents: evidence from event-related potentials

D Zhang, X Zhang, H Ma, Y Wang, H Ma, M Liu - Scientific Reports, 2018 - nature.com
This study used the attention network test (ANT) to evaluate the alerting, orienting, and
executive network efficiencies of attention related to indigenous residents who were born …

Tibetans at extreme altitude

T Wu, S Li, MP Ward - Wilderness & environmental medicine, 2005 - journals.sagepub.com
Between 1960 and 2003, 13 Chinese expeditions successfully reached the summit of
Chomolungma (Mt Everest or Sagarmatha). Forty-five of the 80 summiteers were Tibetan …

Combined fractional anisotropy and subcortical volumetric abnormalities in healthy immigrants to high altitude: A longitudinal study

X Chen, H Li, Q Zhang, J Wang, W Zhang… - Human brain …, 2019 - Wiley Online Library
The study of individuals at high‐altitude (HA) exposure provides an important opportunity for
unraveling physiological and psychological mechanism of brain underlying hypoxia …