[HTML][HTML] Higher VO2max is associated with thicker cortex and lower grey matter blood flow in older adults

G Olivo, J Nilsson, B Garzón, A Lebedev, A Wåhlin… - Scientific Reports, 2021 - nature.com
VO2max (maximal oxygen consumption), a validated measure of aerobic fitness, has been
associated with better cerebral artery compliance and measures of brain morphology, such …

[HTML][HTML] Cardiorespiratory fitness diminishes the effects of age on white matter hyperintensity volume

NF Johnson, AA Bahrani, DK Powell, GA Jicha… - PLoS …, 2020 - journals.plos.org
White matter hyperintensities (WMHs) are among the most commonly observed marker of
cerebrovascular disease. Age is a key risk factor for WMH development. Cardiorespiratory …

[HTML][HTML] Does aerobic exercise influence intrinsic brain activity? An aerobic exercise intervention among healthy old adults

P Flodin, LS Jonasson, K Riklund, L Nyberg… - Frontiers in aging …, 2017 - frontiersin.org
Previous studies have indicated that aerobic exercise could reduce age related decline in
cognition and brain functioning. Here we investigated the effects of aerobic exercise on …

Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults

B Intzandt, D Sabra, C Foster… - Journal of Cerebral …, 2020 - journals.sagepub.com
Aging is accompanied by vascular and structural changes in the brain, which include
decreased grey matter volume (GMV), cerebral blood flow (CBF), and cerebrovascular …

[HTML][HTML] Cardiorespiratory fitness mediates the effects of aging on cerebral blood flow

B Zimmerman, BP Sutton, KA Low… - Frontiers in aging …, 2014 - frontiersin.org
The brain's vasculature is likely to be subjected to the same age-related physiological and
anatomical changes affecting the rest of the cardiovascular system. Since aerobic fitness is …

[HTML][HTML] Aerobic exercise training improves cerebral blood flow and executive function: a randomized, controlled cross-over trial in sedentary older men

JPD Kleinloog, RP Mensink, D Ivanov… - Frontiers in aging …, 2019 - frontiersin.org
Background Physical activity may attenuate age-related cognitive decline by improving
cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic …

Differential associations of engagement in physical activity and estimated cardiorespiratory fitness with brain volume in middle-aged to older adults

DA Raichlen, YC Klimentidis, PK Bharadwaj… - Brain imaging and …, 2020 - Springer
Previous work has confirmed the benefits of aerobic exercise for brain aging, however
mechanisms underlying these effects remain unclear. Two measures of exercise, time spent …

Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults

NF Johnson, BT Gold, AL Bailey, JL Clasey, JG Hakun… - Neuroimage, 2016 - Elsevier
A growing body of evidence indicates that cardiorespiratory fitness attenuates some age-
related cerebral declines. However, little is known about the role that myocardial function …

[HTML][HTML] Physical activity, fitness, and gray matter volume

KI Erickson, RL Leckie, AM Weinstein - Neurobiology of aging, 2014 - Elsevier
In this review, we explore the association among physical activity, cardiorespiratory fitness,
and exercise on gray matter volume in older adults. We conclude that higher …

[HTML][HTML] Physical activity is linked to greater moment-to-moment variability in spontaneous brain activity in older adults

AZ Burzynska, CN Wong, MW Voss, GE Cooke… - PloS one, 2015 - journals.plos.org
Higher cardiorespiratory fitness (CRF) and physical activity (PA) in old age are associated
with greater brain structural and functional integrity, and higher cognitive functioning …