The geometrical increase in diabetes mellitus (DM) and the undesirable side effects of
synthetic drugs have intensified efforts to search for an effective and safe anti-diabetic …

Steroid and painkiller abuse induced peptic ulcer disease, which causes abdominal pain,
fullness, heartburn, and nausea. Medicinal plants have treated ulcers for centuries. We used …

The objective was to predict toxicity on daphnids, fish and rat oral exposure through
quantitative structure activity relationship (QSAR) modelling as well as binding affinity and …

Background Many kinds of orchids have significant health benefits although adequate
research on their biological functions is yet to be carried out. This study investigated the …

Cytochrome P450 enzyme (CYP)-associated metabolic studies in vitro have been
considered cost-effective for predicting potential clinical drug/herb–drug interactions …

Introduction: Peptic ulcer disease (PUD) is one of the most common diseases of the
gastrointestinal tract. Herbal remedies are alternative therapies that have different gastro …

The Aconitum genus is a leading source of a wide range of structurally diverse metabolites
with significant pharmacological implications. The present study investigated metabolite …

As an important part of the comprehensive treatment methods, the urate-lowering Chinese
herbs could provide favorable clinical effects on hyperuricemia in its ability to invigorate …

In the present study, the binding affinity of 52 bioactive secondary metabolites from Wedelia
trilobata towards the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein (PDB: 2W3L) structure …