Class 1 integrons are low-cost structures in Escherichia coli

Y Lacotte, MC Ploy, S Raherison - The ISME Journal, 2017 - academic.oup.com
Resistance integrons are bacterial genetic platforms that can capture and express antibiotic
resistance genes embedded within gene cassettes. The capture and shuffling of gene …

Integron activity accelerates the evolution of antibiotic resistance

C Souque, JA Escudero, RC MacLean - Elife, 2021 - elifesciences.org
Mobile integrons are widespread genetic platforms that allow bacteria to modulate the
expression of antibiotic resistance cassettes by shuffling their position from a common …

High-level gene cassette transcription prevents integrase expression in class 1 integrons

E Guérin, T Jové, A Tabesse, D Mazel… - Journal of …, 2011 - Am Soc Microbiol
Class 1 integrons are widespread genetic elements responsible for dissemination of
antibiotic resistance among Gram-negative bacteria. Integrons allow bacteria to capture and …

The evolutionary dynamics of integrons in changing environments

J Engelstädter, K Harms, PJ Johnsen - The ISME journal, 2016 - academic.oup.com
Integrons are genetic elements that are common in bacteria and are hotspots for genome
evolution. They facilitate the acquisition and reassembly of gene cassettes encoding a …

Gene expression in class 2 integrons is SOS-independent and involves two Pc promoters

T Jové, S Da Re, A Tabesse, A Gassama-Sow… - Frontiers in …, 2017 - frontiersin.org
Integrons are powerful bacterial genetic elements that permit the expression and
dissemination of antibiotic-resistance gene cassettes. They contain a promoter Pc that …

Gene cassettes and cassette arrays in mobile resistance integrons

SR Partridge, G Tsafnat, E Coiera… - FEMS microbiology …, 2009 - academic.oup.com
Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …

An analysis of the evolutionary relationships of integron integrases, with emphasis on the prevalence of class 1 integrons in Escherichia coli isolates from clinical and …

JJ Diaz-Mejia, CF Amabile-Cuevas, I Rosas… - …, 2008 - microbiologyresearch.org
Integrons are genetic elements that allow the mobilization and expression of smaller
elements called gene cassettes, and are considered to be key elements in the evolution of …

Costly Class-1 integrons and the domestication of the the functional integrase

K Harms, I Starikova, PJ Johnsen - Mobile genetic elements, 2013 - Taylor & Francis
Class-1 integrons play an important role in the emergence and spread of antimicrobial
resistance determinants. In a recent study we showed that host fitness was dramatically …

Integrons: natural tools for bacterial genome evolution

DA Rowe-Magnus, D Mazel - Current opinion in microbiology, 2001 - Elsevier
Integrons were first identified as the primary mechanism for antibiotic resistance gene
capture and dissemination among Gram-negative bacteria. More recently, their role in …

Integrons

G Cambray, AM Guerout, D Mazel - Annual review of genetics, 2010 - annualreviews.org
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …