Comprehensive phenotyping in multiple sclerosis: discovery based proteomics and the current understanding of putative biomarkers
KC O'Connor, SM Roy, CH Becker, DA Hafler… - Disease …, 2006 - content.iospress.com
Currently, there is no single test for multiple sclerosis (MS). Diagnosis is confirmed through
clinical evaluation, abnormalities revealed by magnetic resonance imaging (MRI), and …
clinical evaluation, abnormalities revealed by magnetic resonance imaging (MRI), and …
Serum proteomics in multiple sclerosis disease progression
H Tremlett, DLY Dai, Z Hollander, A Kapanen, T Aziz… - Journal of …, 2015 - Elsevier
Multiple sclerosis (MS) is associated with chronic degeneration of the central nervous
system and may cause permanent neurological problems and considerable disability. While …
system and may cause permanent neurological problems and considerable disability. While …
Proteomics technologies for biomarker discovery in multiple sclerosis
V Singh, RQ Hintzen, TM Luider, MP Stoop - Journal of neuroimmunology, 2012 - Elsevier
Multiple sclerosis is a disabling inflammatory and neurodegenerative disorder that
predominantly affects young adults. There is a great need for biomarkers, which could …
predominantly affects young adults. There is a great need for biomarkers, which could …
New technologies for biomarker discovery in multiple sclerosis
M Comabella, MK Racke - Journal of neuroimmunology, 2012 - jni-journal.com
Multiple sclerosis (MS) is a complex and heterogeneous disease in many different aspects,
for example, in its clinical manifestations, disease course, neuroradiological findings …
for example, in its clinical manifestations, disease course, neuroradiological findings …
Cerebrospinal fluid proteomics in multiple sclerosis
AC Kroksveen, JA Opsahl, A Guldbrandsen… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Multiple sclerosis (MS) is an immune mediated chronic inflammatory disease of the central
nervous system usually initiated during young adulthood, affecting approximately 2.5 million …
nervous system usually initiated during young adulthood, affecting approximately 2.5 million …
Ten years of proteomics in multiple sclerosis
Multiple sclerosis, which is the most common cause of chronic neurological disability in
young adults, is an inflammatory, demyelinating, and neurodegenerative disease of the …
young adults, is an inflammatory, demyelinating, and neurodegenerative disease of the …
CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes
ML Elkjaer, A Nawrocki, T Kacprowski, P Lassen… - Scientific reports, 2021 - nature.com
To identify markers in the CSF of multiple sclerosis (MS) subtypes, we used a two-step
proteomic approach:(i) Discovery proteomics compared 169 pooled CSF from MS subtypes …
proteomic approach:(i) Discovery proteomics compared 169 pooled CSF from MS subtypes …
Application of quantitative proteomics technologies to the biomarker discovery pipeline for multiple sclerosis
Multiple sclerosis is an inflammatory‐mediated demyelinating disorder most prevalent in
young C aucasian adults. The various clinical manifestations of the disease present several …
young C aucasian adults. The various clinical manifestations of the disease present several …
Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis
IL Salazar, AST Lourenço, B Manadas… - Journal of …, 2022 - Springer
Background Multiple sclerosis is an inflammatory and degenerative disease of the central
nervous system (CNS) characterized by demyelination and concomitant axonal loss. The …
nervous system (CNS) characterized by demyelination and concomitant axonal loss. The …
Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis
CC Huizar, I Raphael, TG Forsthuber - Cellular immunology, 2020 - Elsevier
Multiple sclerosis (MS) is a neuroinflammatory disorder characterized by autoimmune-
mediated inflammatory lesions in CNS leading to myelin damage and axonal loss. MS is a …
mediated inflammatory lesions in CNS leading to myelin damage and axonal loss. MS is a …