Oxidative stress, which damages cellular components and causes mitochondrial
dysfunction, occurs in a variety of human diseases, including neurological disorders. The …

Astaxanthin is a powerful antioxidant that occurs naturally in a wide variety of living
organisms. The aim of this study is to investigate the effect and the mechanism of …

Astaxanthin, a carotenoid extensively found in marine organisms and increasingly used as a
dietary supplement, has been reported to have neuroprotective effect. In this study, the …

Elevated plasma level of homocysteine (Hcy) represents an independent risk for
neurological diseases, and induction of oxidative damage is considered as one of the most …

Oxidative stress (OS) mediated the pathogenesis of Alzheimer's disease (AD). Astaxanthin
(ATX) has been reported to exert antioxidant activities as well as neuroprotective effects in …

Excitotoxicity is known to associate with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, Amyotrophic lateral sclerosis and Huntington's disease, as …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of
dopaminergic neurons in the substantia nigra pars compacta. Although understanding of the …

Excessive alcohol consumption can lead to brain tissue damage and cognitive dysfunction.
Acetaldehyde, the most toxic metabolite of ethanol, mediates the brain tissue damage and …

Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living
organisms. Much experimental evidence has proved that AST has the function of eliminating …

Oxidative stress is a major contributor to the pathogenesis of various human diseases as
well as to the aging process. Mitochondria, as the center of cellular metabolism and major …