Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis of
tumor cells and their spread to various organs and tissues of body, providing undesirable …

Metastasis is a major cause of morbidity and mortality in patients with cancer. The molecular
mechanisms that control metastasis are related to alterations in various oncogenes, tumor …

STAT3 is both a transcription activator and an oncogene that is tightly regulated under
normal physiological conditions. However, abundant evidence indicates that STAT3 is …

Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic
transcription factor, originally discovered as a transducer of signal from cell surface …

Aberrant Signal transducers and activators of transcription-3 (STAT3) signaling pathway isa
major cause of tumor invasion and metastasis; the underlyingmechanisms, however, are not …

Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription
factor that regulates cell proliferation, differentiation, apoptosis, angiogenesis, inflammation …

Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
transcription factors that mediate intracellular signaling that is usually generated at cell …

Signal transducer and activator of transcription 3 (STAT3), a member of the STAT family,
discovered in the cytoplasm of almost all types of mammalian cells, plays a significant role in …

Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription
factor that modulates the transcription of a variety of genes to regulate important biological …

Numerous cytokines, growth factors, and oncogenic proteins activate signal transducer and
activator of transcription 3 (Stat3), which has been recognized as one of the common …