Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases
MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
Therapeutic progression of quinazolines as targeted chemotherapeutic agents
R Bansal, A Malhotra - European Journal of Medicinal Chemistry, 2021 - Elsevier
Presently cancer is a grave health issue with predominance beyond restrictions. It can affect
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
Bestowal of quinazoline scaffold in anticancer drug discovery
R Das, DK Mehta, M Dhanawat - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background: Cancer is one of the major causes of human mortality worldwide. A number of
existing antineoplastic medications and treatment regimens are already working in the field …
existing antineoplastic medications and treatment regimens are already working in the field …
An insight into the therapeutic potential of quinazoline derivatives as anticancer agents
I Ahmad - MedChemComm, 2017 - pubs.rsc.org
Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …
drugs are available on the market, and several compounds are in different phases of clinical …
Quinazoline derivatives as potential anticancer agents: a patent review (2007–2010)
G Marzaro, A Guiotto, A Chilin - Expert opinion on therapeutic …, 2012 - Taylor & Francis
Introduction: Due to the increase in knowledge about cancer pathways, there is a growing
interest in finding novel potential drugs. Quinazoline is one of the most widespread scaffolds …
interest in finding novel potential drugs. Quinazoline is one of the most widespread scaffolds …
Quinazoline derivatives as anticancer drugs: a patent review (2011–present)
S Ravez, O Castillo-Aguilera, P Depreux… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Quinazoline is one of the most studied moieties in medicinal chemistry due to
the wide range of biological properties such as the anticancer, antibacterial, anti …
the wide range of biological properties such as the anticancer, antibacterial, anti …
Current perspectives on quinazolines with potent biological activities: A review
Quinazoline is a heterocyclic compound having biological activities. It is aromatic in nature
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …
[HTML][HTML] Synthesis, method optimization, anticancer activity of 2, 3, 7-trisubstituted quinazoline derivatives and targeting EGFR-tyrosine kinase by rational approach …
A novel 3-(substituted benzylideneamino)-7-chloro-2-phenyl quinazoline-4 (3H)-one (7–27)
has been synthesized and characterised by IR, 1H NMR, 13C NMR spectroscopy, and …
has been synthesized and characterised by IR, 1H NMR, 13C NMR spectroscopy, and …
[HTML][HTML] Recent advances in 4-aminoquinazoline based scaffold derivatives targeting EGFR kinases as anticancer agents
RSM Ismail, NSM Ismail, S Abuserii… - Future Journal of …, 2016 - Elsevier
Quinazoline derivatives are fused heterocyclic ring systems which have been explored for
their inhibitory activity towards various protein kinase enzymes and their role as anticancer …
their inhibitory activity towards various protein kinase enzymes and their role as anticancer …
Medicinal and biological significance of quinazoline: a highly important scaffold for drug discovery: a review.
A Vijaychand, SN Manjula, EN Bharath, B Divya - 2011 - cabidigitallibrary.org
This article outlines the medicinal and biological significance of one of the most important
heterocycles, the quinazoline. Quinazoline is a highly active scaffold exhibiting wide variety …
heterocycles, the quinazoline. Quinazoline is a highly active scaffold exhibiting wide variety …
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