Schisandrin B suppresses colon cancer growth by inducing cell cycle arrest and apoptosis: Molecular mechanism and therapeutic potential

VA Co, H El-Nezami, Y Liu, B Twum… - ACS Pharmacology & …, 2024 - ACS Publications
Colon cancer is among the most lethal and prevalent malignant tumors in the world, and the
lack of effective therapies highlights the need for novel therapeutic approaches. Schisandrin …

Schisandrin B attenuates colitis-associated colorectal cancer through SIRT1 linked SMURF2 signaling

Z Pu, W Zhang, M Wang, M Xu, H Xie… - The American Journal of …, 2021 - World Scientific
Colon cancer, a common type of malignant tumor, seriously endangers human health.
However, due to the relatively slow progress in diagnosis and treatment, the clinical …

[HTML][HTML] Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells

X Yang, S Wang, Y Mu, Y Zheng - Oncology Reports, 2016 - spandidos-publications.com
Cholangiocarcinoma (CCA) is the second most common hepatic cancer with high resistance
to current chemotherapies and extremely poor prognosis. The present study aimed to …

[HTML][HTML] Schisandrin B inhibits the proliferation of human lung adenocarcinoma A549 cells by inducing cycle arrest and apoptosis

XJ Lv, LJ Zhao, YQ Hao, ZZ Su, JY Li… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer death in the world. Schizandrin B (Sch B) is one
of the main dibenzocyclooctadiene lignans present in the fruit of Schisandra chinensis …

A comprehensive review on schisandrin B and its biological properties

MI Nasser, S Zhu, C Chen, M Zhao… - … Medicine and Cellular …, 2020 - Wiley Online Library
Nature is a vast source of bioactive molecules and has provided an active and efficient
reservoir for drug discovery. Among natural compounds, one of the most promising is …

[HTML][HTML] Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway

X Xu, V Rajamanicham, S Xu, Z Liu, T Yan… - Biomedicine & …, 2019 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer lacking prognostic and
effective therapeutic targets currently. In this study, we evaluated the toxic potential of …

Schisandrin B suppresses gastric cancer cell growth and enhances the efficacy of chemotherapy drug 5-FU in vitro and in vivo

L He, H Chen, Q Qi, N Wu, Y Wang, M Chen… - European Journal of …, 2022 - Elsevier
Gastric cancer (GC) is a serious affliction worldwide and remains to be the fourth most
common cancer with poor prognosis, especially in advanced stage. Chemotherapy is one of …

[HTML][HTML] Schisandrin B inhibits epithelial‑mesenchymal transition and stemness of large‑cell lung cancer cells and tumorigenesis in xenografts via inhibiting the NF‑κB …

S Li, H Wang, R Ma, L Wang - Oncology Reports, 2021 - spandidos-publications.com
Lung cancer is one of the most common types of cancer in the world, resulting in numerous
cancer‑associated deaths. The properties of cancer stem cells (CSCs) are important for the …

Schisandrin B induces apoptosis and cell cycle arrest of gallbladder cancer cells

SS Xiang, XA Wang, HF Li, YJ Shu, RF Bao, F Zhang… - Molecules, 2014 - mdpi.com
Gallbladder cancer, with high aggressivity and extremely poor prognosis, is the most
common malignancy of the bile duct. The main objective of the paper was to investigate the …

[HTML][HTML] Schizandrin A can inhibit non‑small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy

L Zhu, Y Wang, W Lv, X Wu… - International …, 2021 - spandidos-publications.com
Schizandrin A (SchA) can be extracted from the vine plant Schisandra chinensis and has
been reported to confer various biologically active properties. However, its potential …