Immunotherapy for medulloblastoma: current perspectives
TF Kabir, CA Kunos, JL Villano… - ImmunoTargets and …, 2020 - Taylor & Francis
Background Immune-mediated therapies have transformed the treatment of metastatic
melanoma and renal, bladder, and both small and non-small cell lung carcinomas …
melanoma and renal, bladder, and both small and non-small cell lung carcinomas …
[HTML][HTML] Medulloblasoma: challenges for effective immunotherapy
AM Sonabend, AT Ogden, LM Maier… - Journal of neuro …, 2012 - Springer
For medulloblastoma patients, the current therapeutic paradigm of surgery followed by
radiation and chemotherapy can lead to long-term remission. However, the sequelae of …
radiation and chemotherapy can lead to long-term remission. However, the sequelae of …
Immunotherapy in medulloblastoma: current state of research, challenges, and future perspectives
MJ Voskamp, S Li, KR van Daalen, S Crnko… - Cancers, 2021 - mdpi.com
Simple Summary Medulloblastoma (MB) is a primary brain tumor and is one of the most
prevalent neoplasms in the pediatric age group, with a median age of diagnosis of six years …
prevalent neoplasms in the pediatric age group, with a median age of diagnosis of six years …
Cellular immunotherapy for medulloblastoma
MY Schakelaar, M Monnikhof, S Crnko… - Neuro …, 2023 - academic.oup.com
Medulloblastoma (MB) is the most common malignant brain tumor in children, making up~
20% of all primary pediatric brain tumors. Current therapies consist of maximal surgical …
20% of all primary pediatric brain tumors. Current therapies consist of maximal surgical …
[HTML][HTML] Immunosuppression in medulloblastoma: insights into cancer immunity and immunotherapy
Opinion statement Medulloblastoma (MB) is the most common pediatric brain malignancy,
with a 5-year overall survival (OS) rate of around 65%. The conventional MB treatment …
with a 5-year overall survival (OS) rate of around 65%. The conventional MB treatment …
Immune cell landscape and immunotherapy of medulloblastoma
J Zhang, T Wang - Pediatric investigation, 2021 - mednexus.org
Medulloblastoma is the most common primary pediatric malignancy of the central nervous
system. Recurrent and refractory patients account for approximately 30% of them. Immune …
system. Recurrent and refractory patients account for approximately 30% of them. Immune …
Coming in from the cold: overcoming the hostile immune microenvironment of medulloblastoma
T Eisemann, RJ Wechsler-Reya - Genes & Development, 2022 - genesdev.cshlp.org
Medulloblastoma is an aggressive brain tumor that occurs predominantly in children.
Despite intensive therapy, many patients die of the disease, and novel therapies are …
Despite intensive therapy, many patients die of the disease, and novel therapies are …
The current landscape of immunotherapy for pediatric brain tumors
EI Hwang, EJ Sayour, CT Flores, G Grant… - Nature Cancer, 2022 - nature.com
Pediatric central nervous system tumors are the most common solid malignancies in
childhood, and aggressive therapy often leads to long-term sequelae in survivors, making …
childhood, and aggressive therapy often leads to long-term sequelae in survivors, making …
The therapeutic potential of natural killer cells to target medulloblastoma
A Pérez-Martínez, L Fernández… - Expert Review of …, 2016 - Taylor & Francis
Medulloblastoma (MB) is the most common cerebellar neoplasm in the pediatric population.
Treatment is based on multidisciplinary therapy with maximal safe resection surgery …
Treatment is based on multidisciplinary therapy with maximal safe resection surgery …
Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma
JF Vermeulen, W Van Hecke, EJM Adriaansen… - …, 2018 - Taylor & Francis
Pediatric medulloblastomas are the most frequently diagnosed embryonal tumors of the
central nervous system. Current therapies cause severe neurological and cognitive side …
central nervous system. Current therapies cause severe neurological and cognitive side …