[HTML][HTML] Metabolic pathways of the Warburg effect in health and disease: perspectives of choice, chain or chance
JS Burns, G Manda - International journal of molecular sciences, 2017 - mdpi.com
Focus on the Warburg effect, initially descriptive of increased glycolysis in cancer cells, has
served to illuminate mitochondrial function in many other pathologies. This review explores …
served to illuminate mitochondrial function in many other pathologies. This review explores …
The Warburg effect: how does it benefit cancer cells?
MV Liberti, JW Locasale - Trends in biochemical sciences, 2016 - cell.com
Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term
maintenance. The common feature of this altered metabolism is the increased glucose …
maintenance. The common feature of this altered metabolism is the increased glucose …
The Warburg effect: insights from the past decade
Several decades ago, Otto Warburg discovered that cancer cells produce energy
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …
Cellular life span and the Warburg effect
H Kondoh - Experimental cell research, 2008 - Elsevier
Enhanced glycolysis is observed in most of cancerous cells and tissues, called as the
Warburg effect. Recent advance in senescent biology implicates that the metabolic shift to …
Warburg effect. Recent advance in senescent biology implicates that the metabolic shift to …
Drivers of the Warburg phenotype
RA Cairns - The Cancer Journal, 2015 - journals.lww.com
The Warburg effect was first described by Otto Warburg in the 1920s and describes the
preferential conversion of glucose to lactate as opposed to its metabolism through the citric …
preferential conversion of glucose to lactate as opposed to its metabolism through the citric …
[HTML][HTML] Emerging metabolic targets in cancer therapy
Y Zhao, H Liu, AI Riker, O Fodstad… - … in bioscience: a …, 2011 - ncbi.nlm.nih.gov
Cancer cells are different from normal cells in their metabolic properties. Normal cells mostly
rely on mitochondrial oxidative phosphorylation to produce energy. In contrast, cancer cells …
rely on mitochondrial oxidative phosphorylation to produce energy. In contrast, cancer cells …
[HTML][HTML] The Warburg effect 97 years after its discovery
RM Pascale, DF Calvisi, MM Simile, CF Feo, F Feo - Cancers, 2020 - mdpi.com
Simple Summary The deregulation of the oxidative metabolism in cancer cells,
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …
characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv …
Involvement of the Warburg effect in non‐tumor diseases processes
Z Chen, M Liu, L Li, L Chen - Journal of cellular physiology, 2018 - Wiley Online Library
Warburg effect, as an energy shift from mitochondrial oxidative phosphorylation to aerobic
glycolysis, is extensively found in various cancers. Interestingly, increasing researchers …
glycolysis, is extensively found in various cancers. Interestingly, increasing researchers …
The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism
Compared to normal cells, cancer cells strongly upregulate glucose uptake and glycolysis to
give rise to increased yield of intermediate glycolytic metabolites and the end product …
give rise to increased yield of intermediate glycolytic metabolites and the end product …
We need to talk about the Warburg effect
RJ DeBerardinis, NS Chandel - Nature metabolism, 2020 - nature.com
We are approaching the 100th anniversary of Otto Warburg's first description of the
metabolic phenotype bearing his name—a propensity for tumours to metabolize glucose …
metabolic phenotype bearing his name—a propensity for tumours to metabolize glucose …
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