Neurodegenerative disorders are characterized by the progressive dysfunction and death of
selectively vulnerable neuronal populations, often associated with the accumulation of …

Inflammasomes are intracellular protein complexes, members of the innate immune system,
and their activation and regulation play an essential role in maintaining homeostatic …

Neuroinflammation and neurodegeneration often result from the aberrant deposition of
aggregated host proteins, including amyloid‐β, α‐synuclein, and prions, that can activate …

Inflammasomes are molecular scaffolds that are activated by damage-associated and
pathogen-associated molecular patterns and form a key element of innate immune …

Inflammasomes are multimeric protein complexes that can sense a plethora of microbe‐and
damage‐associated molecular signals. They play important roles in innate immunity and are …

Neuroinflammation is a complex innate response of neural tissue against harmful effects of
diverse stimuli viz., pathogens, damaged cells and irritants within the Central Nervous …

Inflammasome activation in the central nervous system occurs in both health and disease.
Inflammasomes are cytosolic protein complexes that sense specific infectious or host stimuli …

Inflammasomes are multiprotein complexes that can sense pathogen‐associated molecular
patterns and damage‐associated molecular signals. They are involved in the initiation and …

Microglia and macrophages in the CNS contain multimolecular complexes termed
inflammasomes. Inflammasomes function as intracellular sensors for infectious agents as …

Recent literature has pointed to the existence of inflammasome-mediated inflammatory
pathways in central nervous system (CNS) disorders and associated changes in behavior …