Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse
bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti …

Background Ischemia reperfusion injury (IRI) is unavoidable in liver transplantation and
hepatectomy. The present study aimed to explore the possible mechanism and the effect of …

Background/Aims: Ischemia-reperfusion (I/R) adversely affects the intestinal mucosa. The
major mechanisms of I/R are the generation of reactive oxygen species (ROS) and …

Severe steatosis in donor livers is contraindicated for transplantation due to the high risk of
ischemia–reperfusion injury (IRI). Although Ho-1 gene-modified bone marrow mesenchymal …

Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several
clinical situations. Modulating oxidative stress and inflammation by Nrf2/HO-1 and …

Results The serum aminotransferases, hepatic MDA concentration, and apoptotic cells in the
IR group were significantly higher than in the sham group (p< 0.01), whereas the Sal-A …

Sepsis causes severe dysregulation of organ functions, via the development of oxidative
stress and inflammation. These pathophysiological mechanisms are mimicked in mice …

Oxidative stress, inflammation, and apoptosis are crucial in the pathogenesis of acute liver
failure (ALF). 4‐Octyl itaconate (OI) showed antioxidative and anti‐inflammatory properties …

Background: It has been reported that intestinal ischemia‐reperfusion injury (IIRI) is closely
related to inflammatory response, apoptosis and oxidative stress. Ellagic acid (EA) has been …

Rosmarinic acid (RA) is a natural polyphenol with various biological activities, such as anti-
oxidative, anti-fibrotic, and hepatoprotective properties. The objective of this study was to …