Bridging the species gap in translational research for neurodevelopmental disorders
The prevalence and societal impact of neurodevelopmental disorders (NDDs) continue to
increase despite years of research in both patient populations and animal models. There …
increase despite years of research in both patient populations and animal models. There …
Improving treatment of neurodevelopmental disorders: recommendations based on preclinical studies
JR Homberg, EJ Kyzar, AM Stewart… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Neurodevelopmental disorders (NDDs) are common and severely debilitating.
Their chronic nature and reliance on both genetic and environmental factors makes studying …
Their chronic nature and reliance on both genetic and environmental factors makes studying …
Reversing neurodevelopmental disorders in adults
Abnormalities in brain development, thought to be irreversible in adults, have long been
assumed to underlie the neurological and psychiatric symptoms associated with …
assumed to underlie the neurological and psychiatric symptoms associated with …
Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models
Neurodevelopmental disorders (NDDs) are highly prevalent and severely debilitating brain
illnesses caused by aberrant brain growth and development. Resulting in cognitive, social …
illnesses caused by aberrant brain growth and development. Resulting in cognitive, social …
Genetic and environmental modulation of neurodevelopmental disorders: translational insights from labs to beds
Neurodevelopmental disorders (NDDs) are a heterogeneous group of prevalent
neuropsychiatric illnesses with various degrees of social, cognitive, motor, language and …
neuropsychiatric illnesses with various degrees of social, cognitive, motor, language and …
Neurodevelopmental Disorders, Causes, and Consequences
EH Sherr - Genomics, Circuits, and Pathways in Clinical …, 2016 - Elsevier
In the overlap between the fields of neurology, psychiatry, and pediatrics, it may be hard to
find a term with as much generality as neurodevelopmental disorders (NDD). Not …
find a term with as much generality as neurodevelopmental disorders (NDD). Not …
Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies
CM McGraw, CS Ward… - American Journal of …, 2017 - Wiley Online Library
Neurobehavioral disorders comprised of neurodegenerative, neurodevelopmental, and
psychiatric disorders together represent leading causes of morbidity and mortality. Despite …
psychiatric disorders together represent leading causes of morbidity and mortality. Despite …
The clinical-basic interface in defining pathogenesis in disorders of neurodevelopmental origin
BL Thompson, P Levitt - Neuron, 2010 - cell.com
Human cognitive and social-emotional behaviors are heterogeneous, underscoring the
challenges in modeling pathogenesis in disorders of neurodevelopmental origin in which …
challenges in modeling pathogenesis in disorders of neurodevelopmental origin in which …
Modelling behaviors relevant to brain disorders in the nonhuman primate: Are we there yet?
JT Scott, JA Bourne - Progress in Neurobiology, 2022 - Elsevier
Recent years have seen a profound resurgence of activity with nonhuman primates (NHPs)
to model human brain disorders. From marmosets to macaques, the study of NHP species …
to model human brain disorders. From marmosets to macaques, the study of NHP species …
Zebrafish as a model of neurodevelopmental disorders
Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development
are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are …
are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are …