Development of germinal center (GC) B cells and follicular helper T (Tfh) cells requires the
transcription factor B‐cell lymphoma 6 (Bcl6). Expression of Bcl6 in B cells and helper T cells …

The transcription factor Bcl6 is essential for the development of germinal center (GC) B cells
and follicular helper T (Tfh) cells. However, little is known about in vivo dynamics of Bcl6 …

Abstract Follicular helper T (T FH) cells, defined by expression of the surface markers
CXCR5 and programmed death receptor-1 (PD-1) and synthesis of IL-21, require …

Abstract T follicular helper (T FH) cells are central to the development and regulation of T
cell-dependent humoral immune responses. The transcriptional repressor BCL6 is required …

BCL6 is a transcriptional repressor required in mature B cells during the germinal center
(GC) reaction. Multiple mechanisms act coordinately to timely modulate BCL6 expression at …

It is unknown whether the incremental increases in BCL6 amounts in antigen-activated B
cells influence the unfolding differentiation before germinal center (GC) formation. By …

The BCL6 oncogenic repressor is a master regulator of humoral immunity and B-cell
lymphoma survival. Whereas much research has focused on its regulation and function in …

Follicular helper T cells (T FH) are essential B cell-help providers in the formation of
germinal centers (GCs), affinity maturation of GC B cells, differentiation of high-affinity …

Follicular helper T cells (Tfh cells) are required for T cell help to B cells, and BCL6 is the
defining transcription factor of Tfh cells. However, the functions of BCL6 in Tfh cells have …

The transcriptional repressor BCL6 plays an essential role in the development of germinal
center B cells and follicular helper T cells. However, much less is known about the …