Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs

PE Almeida Da Silva… - Journal of antimicrobial …, 2011 - academic.oup.com
Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …

Drug Resistance Mechanisms in Mycobacterium tuberculosis

JC Palomino, A Martin - Antibiotics, 2014 - mdpi.com
Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …

Molecular Biology of Drug Resistance in Mycobacterium tuberculosis

T Smith, KA Wolff, L Nguyen - … tuberculosis and its Interaction with the …, 2012 - Springer
Tuberculosis (TB) has become a curable disease, thanks to the discovery of antibiotics.
However, it has remained one of the most difficult infections to treat. Most current TB …

Molecular genetics of drug resistance in Mycobacterium tuberculosis

Y Zhang, D Young - Journal of Antimicrobial Chemotherapy, 1994 - academic.oup.com
Tuberculosis (TB) is the single largest killer among infectious diseases. The recent
resurgence of TB together with outbreaks of multidrug resistant tuberculosis has focused …

Evolution of Drug Resistance in Mycobacterium tuberculosis: Clinical and Molecular Perspective

SH Gillespie - Antimicrobial agents and chemotherapy, 2002 - Am Soc Microbiol
The story of antituberculosis chemotherapy is a miniature of the history of anti-infective
chemotherapy. In the first half of the 20th century the problem of tuberculosis appeared …

Drug resistant Tuberculosis: A review

JL Khawbung, D Nath, S Chakraborty - … immunology, microbiology and …, 2021 - Elsevier
Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …

Mechanisms of Drug Resistance in Mycobacterium tuberculosis

Y Zhang, C Vilchèze… - Tuberculosis and the …, 2004 - Wiley Online Library
Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug …

13 Mechanism of Drug Resistance in Mycobacterium tuberculosis

AS Pym, ST Cole - Bacterial Resistance to Antimicrobials, 2007 - books.google.com
Tuberculosis is the leading cause of death from a curable infectious disease and there were
an estimated 8.9 million new cases of tuberculosis in 2004 [1]. Tackling the global burden of …

Drug resistance in Mycobacterium tuberculosis

R Johnson, EM Streicher, GE Louw… - Current issues in …, 2006 - mdpi.com
Anti-tuberculosis drugs are a two-edged sword. While they destroy pathogenic M.
tuberculosis they also select for drug resistant bacteria against which those drugs are then …

Multidrug-resistant Mycobacterium tuberculosis: molecular perspectives.

A Rattan, A Kalia, N Ahmad - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
Multidrug-resistant strains of Mycobacterium tuberculosis seriously threaten tuberculosis
(TB) control and prevention efforts. Molecular studies of the mechanism of action of …