Endothelial-immune cell cross-talk goes well beyond leukocyte and lymphocyte trafficking,
since immune cells are able to intimately regulate vessel formation and function. Here we …

Angiogenesis, the formation of new blood vessels, as well as inflammation with massive
infiltration of leukocytes are hallmarks of various tumor entities. Various epidemiological …

It is widely accepted that the tumor microenvironment (TUMIC) plays a major role in cancer
and is indispensable for tumor progression. The TUMIC involves many “players” going well …

The critical role of angiogenesis in promoting tumor growth and metastasis is strongly
established. However, tumors show considerable variation in angiogenic characteristics and …

Malignant cells thrive in a highly specialized, stromal environment, which harbors support
cells, blood vessels, and diverse leukocyte populations. There is increasing evidence that …

Tumor angiogenesis and escape of immunosurveillance are two cancer hallmarks that are
tightly linked and reciprocally regulated by paracrine signaling cues of cell constituents from …

Introduction• The importance of angiogenesis in physiological and pathological conditions•
The contribution of immune cells to angiogenesis in inflammation and tumour growth• …

Simple Summary A clinical decision and study design investigating the level and extent of
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic …

Research over the last decades has provided strong evidence for the pivotal role of the
tumor-associated blood and lymphatic vasculature in supporting immunoevasion and in …

During carcinogenesis, advanced tumors are surrounded by both stromal and immune cells,
which support tumor development. In addition, inflammation and angiogenesis are …