Altered Subcellular Distribution of the 75‐kD a DISC 1 Isoform, cAMP Accumulation, and Decreased Neuronal Migration in Schizophrenia and Bipolar Disorder …
J Muñoz‐Estrada, G Benítez‐King… - CNS Neuroscience …, 2015 - Wiley Online Library
Summary Background DISC 1 (Disrupted‐In‐Schizophrenia‐1) is considered a genetic risk
factor for schizophrenia (SZ) and bipolar disorder (BD). DISC 1 regulates microtubule …
factor for schizophrenia (SZ) and bipolar disorder (BD). DISC 1 regulates microtubule …
Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus
KD Meyer, JA Morris - Gene Expression Patterns, 2008 - Elsevier
In recent years, Disrupted-In-Schizophrenia 1 (DISC1) has emerged as one of the most
promising candidate genes whose disruption confers an increased risk for schizophrenia …
promising candidate genes whose disruption confers an increased risk for schizophrenia …
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions
K Ishizuka, M Paek, A Kamiya, A Sawa - Biological psychiatry, 2006 - Elsevier
Disrupted-In-Schizophrenia-1 (DISC1) is a promising candidate gene for schizophrenia (SZ)
and bipolar disorder (BP), but its basic biology remains to be elucidated. Accumulating …
and bipolar disorder (BP), but its basic biology remains to be elucidated. Accumulating …
Disc1 point mutations in mice affect development of the cerebral cortex
FHF Lee, MP Fadel, K Preston-Maher… - Journal of …, 2011 - Soc Neuroscience
Disrupted-in-Schizophrenia 1 (DISC1) is a strong candidate gene for schizophrenia and
other mental disorders. DISC1 regulates neurodevelopmental processes including …
other mental disorders. DISC1 regulates neurodevelopmental processes including …
Regulation of the cytoskeleton by Disrupted-in-schizophrenia 1 (DISC1)
Q Wang, NJ Brandon - Molecular and Cellular Neuroscience, 2011 - Elsevier
Disrupted in schizophrenia 1 (DISC1) is one of the strongest supported risk genes for
psychiatric disorders, such as schizophrenia, major depression, bipolar disorder, and …
psychiatric disorders, such as schizophrenia, major depression, bipolar disorder, and …
DISC1 in schizophrenia: genetic mouse models and human genomic imaging
M Johnstone, PA Thomson, J Hall… - Schizophrenia …, 2011 - academic.oup.com
Schizophrenia and related disorders have a major genetic component. Several large-scale
studies have uncovered a number of possible candidate genes, but these have yet to be …
studies have uncovered a number of possible candidate genes, but these have yet to be …
Disrupted-in-Schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons
A Steinecke, C Gampe, C Valkova… - Journal of …, 2012 - Soc Neuroscience
Disrupted-in-Schizophrenia 1 (DISC1) is a prominent susceptibility gene for major
psychiatric disorders. Previous work indicated that DISC1 plays an important role during …
psychiatric disorders. Previous work indicated that DISC1 plays an important role during …
Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly
S Narayanan, H Arthanari, MS Wolfe… - Journal of Biological …, 2011 - ASBMB
DISC1 (Disrupted in schizophrenia-1) plays essential roles in neuronal proliferation,
neuronal migration and axon guidance and has been implicated in schizophrenia and …
neuronal migration and axon guidance and has been implicated in schizophrenia and …
Disc1 regulates granule cell migration in the developing hippocampus
KD Meyer, JA Morris - Human molecular genetics, 2009 - academic.oup.com
Schizophrenia is a severely debilitating psychiatric disease that is hypothesized to have its
roots in neurodevelopment. Although the precise neuropathology underlying schizophrenia …
roots in neurodevelopment. Although the precise neuropathology underlying schizophrenia …
Genes and Schizophrenia: Beyond Schizophrenia: The Role of DISC1 in Major Mental Illness
W Hennah, P Thomson, L Peltonen… - Schizophrenia …, 2006 - academic.oup.com
Schizophrenia and related disorders have a major genetic component, but despite much
effort and many claims, few genes have been consistently replicated and fewer have …
effort and many claims, few genes have been consistently replicated and fewer have …