[HTML][HTML] PR-SET7 epigenetically restrains uterine interferon response and cell death governing proper postnatal stromal development
H Bao, Y Sun, N Deng, L Zhang, Y Jia, G Li… - Nature …, 2024 - nature.com
The differentiation of the stroma is a hallmark event during postnatal uterine development.
However, the spatiotemporal changes that occur during this process and the underlying …
However, the spatiotemporal changes that occur during this process and the underlying …
[HTML][HTML] PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice
T Cui, B He, S Kong, C Zhou, H Zhang, Z Ni… - Cell Death & …, 2017 - nature.com
Formation of secretary endometrial glands in the uterus known as adenogenesis is a typical
process of branching morphogenesis involving dynamic epithelial growth and differentiation …
process of branching morphogenesis involving dynamic epithelial growth and differentiation …
[HTML][HTML] Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling
M Liu, W Deng, L Tang, M Liu, H Bao, C Guo… - Nature …, 2022 - nature.com
During decidualization in rodents, uterine stroma undergoes extensive reprograming into
distinct cells, forming the discrete regions defined as the primary decidual zone (PDZ), the …
distinct cells, forming the discrete regions defined as the primary decidual zone (PDZ), the …
Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage
X Zhou, Y Xu, S Ren, N Yang, Y Sun… - Proceedings of the …, 2023 - National Acad Sciences
Recurrent miscarriage (RM) is a distressing pregnancy complication. While the etiology of
RM remains unclear, growing evidence has indicated the relevance of trophoblast …
RM remains unclear, growing evidence has indicated the relevance of trophoblast …
[HTML][HTML] Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
I Osokine, J Siewiera, D Rideaux, S Ma, T Tsukui… - Cell reports, 2022 - cell.com
A little-appreciated feature of early pregnancy is that embryo implantation and placental
outgrowth do not evoke wound-healing responses in the decidua, the specialized …
outgrowth do not evoke wound-healing responses in the decidua, the specialized …
[HTML][HTML] H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition
P Nancy, J Siewiera, G Rizzuto… - The Journal of …, 2018 - Am Soc Clin Investig
Uncovering the causes of pregnancy complications such as preterm labor requires greater
insight into how the uterus remains in a noncontractile state until term and then surmounts …
insight into how the uterus remains in a noncontractile state until term and then surmounts …
[HTML][HTML] Estrogen-induced expression of Fos-related antigen 1 (FRA-1) regulates uterine stromal differentiation and remodeling
Concerted actions of estrogen and progesterone via their cognate receptors orchestrate
changes in the uterine tissue, regulating implantation during early pregnancy. The uterine …
changes in the uterine tissue, regulating implantation during early pregnancy. The uterine …
Early growth response 1 transcriptionally primes the human endometrial stromal cell for decidualization
Mouse studies support a role for endometrial early growth response 1 (EGR1) in uterine
receptivity and decidualization, which are processes controlled by estrogen and …
receptivity and decidualization, which are processes controlled by estrogen and …
H3K27me3 timely dictates uterine epithelial transcriptome remodeling and thus transformation essential for normal embryo implantation
Uterine luminal epithelia (LE), the first layer contacting with the blastocyst, acquire receptivity
for normal embryo implantation. Besides the well-accepted transcriptional regulation …
for normal embryo implantation. Besides the well-accepted transcriptional regulation …
[HTML][HTML] Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution
M Liu, M Ji, J Cheng, Y Li, Y Tian, H Zhao… - Nature …, 2023 - nature.com
The timely onset of female parturition is a critical determinant for pregnancy success. The
highly heterogenous maternal decidua has been increasingly recognized as a vital factor in …
highly heterogenous maternal decidua has been increasingly recognized as a vital factor in …