Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …

Therapeutic cancer vaccines require robust cellular immunity for the efficient killing of tumor
cells, and recent advances in neoantigen discovery may provide safe and promising targets …

Massage RNA (mRNA) vaccines represent a new strategy for advanced cancer
immunotherapy. To protect mRNA from degradation and deliver to targeted cells, lipid …

With an intensive understanding of the mechanism of immune system, developing a
therapeutic tumor vaccine is one of the most perspective strategy of cancer immunotherapy …

For efficient cancer vaccines, the antitumor function largely relies on cytotoxic T cells, whose
activation can be effectively induced via antigen-encoding mRNA, making mRNA-based …

Benefiting from their unique physicochemical properties, graphene derivatives have
attracted great attention in biomedicine. In this study, we carefully engineered graphene …

Tapping into the innate immune system's power, nanovaccines can induce tumor-specific
immune responses, which is a promising strategy in cancer immunotherapy. However …

Immunotherapy in solid tumors is limited by the poor immunogenicity of tumors and limited T-
cell immune response, resulting in low patient response rate. To increase the efficiency of …

Tumor vaccine has been one of the research hotspots for cancer immunotherapy in recent
years. By introducing tumor antigens into the body, the patient's own immune system will be …

Vaccination shows great promise in cancer immunotherapy. However, the induction of
robust and broad therapeutic CD8 T cell immunity against tumors is challenging due to the …