With a single gene encoding HV1 channel, proton channel diversity is particularly low in
mammals compared to other members of the superfamily of voltage-gated ion channels …

In this review, voltage-gated proton channels are considered from a mainly teleological
perspective. Why do proton channels exist? What good are they? Why did they go to such …

Voltage-gated proton channels (HV) are unique, in part because the ion they conduct is
unique. HV channels are perfectly selective for protons and have a very small unitary …

Voltage‐gated proton selective channels occupy an ill‐defined region between “normal” ion
channels and a variety of proton‐conducting pathways inside proteins, including, but not …

The voltage-gated proton channel, Hv1, is expressed in blood cells, airway epithelium,
sperm and microglia, playing important roles in diverse biological contexts including …

The existence of a proton-selective pathway through a protein is a common feature of
voltage-gated proton channels and a number of molecules that play pivotal roles in …

Introduction 3. Features shared by all voltage-gated proton channels 3.1. Voltage-
dependent gating 3.2. The voltage dependence of gating is modulated strongly by pHo and …

The voltage‐gated proton channel 1 (HV 1) is an important component of the cellular proton
extrusion machinery and is essential for charge compensation during the respiratory burst of …

Voltage-gated proton (Hv) channels play an essential role in phagocytic cells by generating
a hyperpolarizing proton current that electrically compensates for the depolarizing current …

Significance: Voltage-gated proton channels are increasingly implicated in cellular proton
homeostasis. Proton currents were originally identified in snail neurons less than 40 years …