Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …

Abstract Isoprostanes (IsoPs) and neuroprostanes (NeuroPs) are formed in vivo by a free
radical non-enzymatic mechanism involving peroxidation of arachidonic acid (AA, C20: 4 n …

The isoprostanes are a new class of natural products produced in vivo by a non-enzymatic
free-radical-induced peroxidation of polyunsaturated fatty acid. In the case of arachidonic …

The isoprostanes (IsoPs) are a unique series of prostaglandin-like compounds formed in
vivo via a nonenzymatic mechanism involving the free radical-initiated peroxidation of …

Isoprostanes (IsoPs) are prostaglandin-like molecules generated independent of the
cyclooxygenase (COX) by the free radical-induced peroxidation of arachidonic acid. The first …

Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …

We previously reported the discovery of prostaglandin F 2-like compounds (F 2-
isoprostanes) formed by nonenzymatic free-radical-induced peroxidation of arachidonic …

Some years ago it was discovered that prostaglandin F2‐like compounds are formed in vivo
by nonenzymatic free radical‐catalyzed peroxidation of arachidonic acid. Because these …

Isoprostanes (IsoPs) are isomers of prostaglandins that are generated from the free radical-
initiated peroxidation of arachidonic acid (C20. 4 ω-6). IsoPs exert potent bioactivity and are …

Free radicals derived primarily from molecular oxygen have been implicated in a variety of
human disorders including atherosclerosis, cancer, neurodegenerative diseases, and aging …