The abnormal misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet enriched
insoluble deposits initiates a cascade of events leading to pathological processes and …

Alzheimer's disease (AD) involves amyloid β (Aβ) accumulation, oxidative damage, and
inflammation, and risk is reduced with increased antioxidant and anti-inflammatory …

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's
disease (AD). The size and density of these plaques are closely associated with cognitive …

Amyloid plaques and neurofibrillary tangles are the hallmarks of Alzheimer's disease.
Amyloid β, a primary component of the amyloid plaques, is neurotoxic. Considerable …

Alzheimer's disease (AD) is characterized by senile plaques and neurodegeneration
although the neurotoxic mechanisms have not been completely elucidated. It is clear that …

Amyloid-β peptide (Aβ)–membrane interactions have been implicated in the formation of
toxic oligomers that permeabilize membranes, allowing an influx of calcium ions and …

Alzheimer disease (AD) is a devastating neurodegenerative disease with no cure. The
pathogenesis of AD is believed to be driven primarily by amyloid-β (Aβ), the principal …

Abstract Alzheimer's disease (AD), a neurodegenerative disorder exhibiting progressive loss
of memory and cognitive functions, is characterized by the presence of neuritic plaques …

Amyloidosis is a concept that implicates disorders and complications that are due to
abnormal protein accumulation in different cells and tissues. Protein aggregation …

Background Neuroinflammation and the presence of amyloid beta protein (Aβ) and
neurofibrillary tangles are key pathologies in Alzheimer's disease (AD). As a potent anti …