Gallium radiopharmaceutical chemistry

MA Green, MJ Welch - International Journal of Radiation Applications and …, 1989 - Elsevier
There are two gallium radioisotopes, 67Ga and 68Ga, possessing nuclear properties”'that
make them attractive for use in nuclear medicine (Table 1). The first, 67Ga, is cyclotron …

Gallium-68: a new trend in PET radiopharmacy

IM Prata - Current radiopharmaceuticals, 2012 - ingentaconnect.com
The most common PET radioisotopes, both in the literature and in clinical practice, are the
cyclotron produced 11C and 18F, giving rise to tracers with minimal chemical changes with …

A new generator for ionic gallium-68.

C Loc'h, B Maziere, D Comar - Journal of Nuclear Medicine: Official …, 1980 - europepmc.org
To meet the needs created by the rapid development of positron tomographic techniques, a
new Ge-68 leads to Ga-68 generator has been developed. By elution under reduced …

Comparison of 68Ge/68Ga generator systems for radiopharmaceutical production

KD McElvany, KT Hopkins, MJ Welch - The International journal of applied …, 1984 - Elsevier
Abstract Three 68 Ge/68 Ga generators have been evaluated over a period of 1 yr; the
systems were compared with respect to 68 Ga elution profiles and yields, parent 68 Ge …

The medical use of gallium radionuclides: a brief history with some comments

RL Hayes - Seminars in nuclear medicine, 1978 - Elsevier
The use of gallium radionuclides in nuclear medicine dates back to the late 1940s, following
the observation in toxicologic studies that gallium tended to localize to a high degree at sites …

Gallium-67 and indium-111 radiopharmaceuticals

ML Thakur - The International journal of applied radiation and …, 1977 - Elsevier
There are no compounds known to exist naturally in the human body which involve gallium
or indium metal cofactors. In spite of this numerous compounds which contain 67 Ga and …

The current status of the production and supply of gallium-68

K Kumar - Cancer biotherapy & radiopharmaceuticals, 2020 - liebertpub.com
Gallium-68 (68Ga) is an important radionuclide due to its successful use in the clinic.
Currently, 68Ga is produced and supplied by using germanium-68/Gallium-68 (68Ge/68Ga) …

Gallium-68 in medical imaging

L Martiniova, LD Palatis, E Etchebehere… - Current …, 2016 - ingentaconnect.com
Over the past several years, Positron Emission Tomography (PET) imaging agents labeled
with 68Gallium (68Ga) have undergone a significant increase in clinical utilization. 68Ga is …

Production and purification of gallium-66 for preparation of tumor-targeting radiopharmaceuticals

MR Lewis, DE Reichert, R Laforest… - Nuclear medicine and …, 2002 - Elsevier
Gallium-66 (T1/2= 9.49 h) is an intermediate-lived radionuclide that has potential for positron
emission tomography (PET) imaging of biological processes with intermediate to slow target …

Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …