A direct and general method for the synthesis of naturally occurring 2, 3, 4, 5, 6-
pentasubstituted tetrahydropyrans has been developed, employing β, γ-unsaturated N-acyl …

A general and stereoselective method to synthesize 2, 3, 4, 5, 6-pentasubstituted
tetrahydropyrans in three steps starting from three different aldehydes is described. Key …

The reaction of aldehyde with homoallyl alcohols mediated by indium trichloride generated
4-chlorotetrahydropyrans in high yields and with high stereoselectivity. The same type of …

A simple, efficient and highly diastereoselective one-pot three-component synthesis of
functionalized 2, 6-disubstituted-4-tosyloxytetrahydropyrans was performed. The synthesis …

A diastereoselective synthesis of cis-2, 6-disubstituted tetrahydropyran-4-ones was
developed. The key step of this methodology, a silyl enol ether Prins cyclization, was …

A modular enantioselective synthesis of spiroketals, spiroethers, and oxabicycles, each
containing a dihydropyran subunit, is described. It is based on the 2, 2‐spiro‐and 2, 6 …

Thieme E-Journals - SynOpen / Full Text DE EN Home Products Journals Books Book
Series Service Library Service Help Contact Portal SynOpen Full-text search Full-text …

A convenient and diastereoselective one-pot synthesis of cis-4-amidotetrahydropyrans is
described. This simple protocol involves Prins cyclization of homoallylic alcohol and …

We have described a highly diastereoselective synthesis of 2, 6-disubstituted 4-
(dimethoxymethyl) tetrahydropyrans via TMSOTf-promoted Prins–pinacol reaction of …

Three-component coupling of carbonyl compounds, homoallylic alcohols, and nitriles has
been achieved using 20mol% of phosphomolybdic acid (PMA) at ambient temperature via …