Background During periodontitis, tooth‐supporting alveolar bone is resorbed when there is
an increased expression of the pro‐osteolytic factor termed receptor activator of nuclear …

Periodontitis is a bacterially-induced inflammatory disease that leads to tooth loss. It results
from the damaging effects of a dysregulated immune response, mediated largely by …

Purpose Several substances that have anti-inflammatory, antiproteinase, and anti-infective
properties have been evaluated as modulators of the inflammatory response in periodontal …

Background Persistent host immune responses initiated by oral bacteria protect host against
infection but may also elicit the process of sustained periodontal inflammation and …

Aim Periodontitis is a prevalent oral immunoinflammatory condition that is distinguished by
the compromised functionality of periodontal ligament stem cells (PDLSCs). Bomidin, a new …

Periodontal disease characterized by alveolar bone resorption and bacterial pathogen‐
evoked inflammatory response has been believed to have an important impact on human …

Background and Objective Periodontitis is a bacteria‐induced disease that often leads to
alveolar bone damage. Its mechanisms were considered to be complicated, involving an …

Aim To determine the effects of RVX‐208, a selective bromodomain and extra‐terminal
domain (BET) inhibitor targeting bromodomain 2 (BD2), on periodontal inflammation and …

Periodontitis is a bacteria-induced disease that always clinically defined as loss of
attachment, periodontal pocket and bone loss. Its mechanisms were considered to be …

Objective Periodontitis, one of the most prevalent chronic oral infectious diseases in
humans, is induced by the breakdown in the balance between the biofilm and host immune …