LasB (elastase/pseudolysin) is an injurious zinc-metalloprotease secreted by the infecting
Pseudomonas aeruginosa. LasB is recognized as the bacterial key virulence factor for …

Antimicrobial resistance (AMR; see Glossary) is recognised as a major global threat to
public health 1, 2, 3. Antibiotics are a mainstay of modern healthcare, treating and …

LasB elastase is a broad-spectrum exoprotease and a key virulence factor of Pseudomonas
aeruginosa, a major pathogen causing lung damage and inflammation in acute and chronic …

LasA is an extracellular protease of Pseudomonas aeruginosa that enhances the elastolytic
activity of Pseudomonas elastase and other proteases by cleaving elastin at unknown sites …

The human pathogen Pseudomonas aeruginosa has a number of virulence factors at its
disposal that play crucial roles in the progression of infection. LasB is one of the major …

The LasA protease of Pseudomonas aeruginosa can degrade elastin and is an important
contributor to the pathogenesis of this organism. LasA (20 kDa) is a member of the beta-lytic …

Proteolytic enzymes constitute one of the most important groups of industrial enzymes and
have received worldwide attention due to their wide range of biotechnological applications …

Pseudomonas aeruginosa is a non-fermentative, gram-negative bacterium that is one of the
most common pathogens responsible for hospital-acquired infections worldwide. The …

LasA protease is a 20-kDa elastolytic and staphylolytic enzyme secreted by Pseudomonas
aeruginosa. LasA is synthesized as a preproenzyme that undergoes proteolysis to remove a …

The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe
and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence …