Thrombomodulin (TM) is an integral membrane protein expressed on the surface of vascular
endothelial cells that suppresses blood coagulation. Recent studies have shown that TM …

Thrombomodulin (TM) is a vascular endothelial cell (EC) receptor that is a cofactor for
thrombin-mediated activation of the anticoagulant protein C. The extracellular NH2-terminal …

The leukocyte adhesion cascade involves multiple events that efficiently localize circulating
leukocytes into the injured sites to mediate inflammatory responses. From rolling to firm …

Thrombomodulin (TM) is expressed on the surface of monocyte, which is important in the
regulation of cell migration, proliferation, and inflammatory responses. In a previous study …

Objective—The N-terminal lectin-like domain (domain 1 [D1]) of thrombomodulin (TM) is
known to have an anti-inflammatory function. We previously showed that recombinant TM …

Endothelial cellular stiffening has been observed not only in inflamed cultured endothelial
cells but also in the endothelium of atherosclerotic regions, which is an underlying cause of …

Thrombomodulin (TM) is a thrombin receptor on endothelial cells that is involved in
promoting activation of the anticoagulant protein C pathway during blood coagulation. TM …

We reported previously that leukocyte β2 integrins (LFA-1 and Mac-1) bind to the
serine/threonine-rich domain of thrombomodulin (TM) expressed on vascular endothelial …

Background Thrombomodulin (TM), a transmembrane glycoprotein highly expressed in
endothelial cells (ECs), is a potent anticoagulant maintaining circulation homeostasis. Under …

Thrombomodulin (TM) is a membrane-bound glycoprotein receptor r thrombin in the protein
C activation pathway. Since its discovery in the 1980s as an anticoagulant protein, recent …