H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

Q Chen, C Liang, X Sun, J Chen… - Proceedings of the …, 2017 - National Acad Sciences
Abnormal H2O2 levels are closely related to many diseases, including inflammation and
cancers. Herein, we simultaneously load HRP and its substrate, 2, 2′-azino-bis (3 …

Quantitative photoacoustic diagnosis and precise treatment of inflammation in vivo using activatable theranostic nanoprobe

J Ye, Z Li, Q Fu, Q Li, X Zhang, L Su… - Advanced Functional …, 2020 - Wiley Online Library
Excessive production of reactive oxygen species such as H2O2 is the pathological basis of
chronic inflammatory diseases, as well as bacterial infection‐induced inflammation …

A self‐assembled albumin‐based nanoprobe for in vivo ratiometric photoacoustic pH imaging

Q Chen, X Liu, J Chen, J Zeng, Z Cheng… - Advanced …, 2015 - Wiley Online Library
DOI: 10.1002/adma. 201503194 needed to develop an accurate and easy-to-operate
method for real-time in vivo noninvasive pH imaging. Different from fluorescence imaging …

Microenvironment‐Tailored Catalytic Nanoprobe for Ratiometric NIR‐II Fluorescence/Photoacoustic Imaging of H2O2 in Tumor and Lymphatic Metastasis

T Chen, Z Chen, Q Zhou, H Ding… - Advanced Functional …, 2022 - Wiley Online Library
In vivo H2O2 visualization is crucial for disease diagnosis. Catalytic reaction‐based probes
show potential in H2O2 detection, yet their in vivo application remains challenging because …

Exosome-like Nanozyme Vesicles for H2O2-Responsive Catalytic Photoacoustic Imaging of Xenograft Nasopharyngeal Carcinoma

H Ding, Y Cai, L Gao, M Liang, B Miao, H Wu, Y Liu… - Nano …, 2018 - ACS Publications
Photoacoustic imaging (PAI) is an attractive imaging modality, which is promising for clinical
cancer diagnosis due to its advantages on deep tissue penetration and fine spatial …

In vivo quantitative imaging of tumor pH by nanosonophore assisted multispectral photoacoustic imaging

J Jo, CH Lee, R Kopelman, X Wang - Nature communications, 2017 - nature.com
Abstract Changes of physiological pH are correlated with several pathologies, therefore the
development of more effective medical pH imaging methods is of paramount importance …

pH-sensitive and biodegradable charge-transfer nanocomplex for second near-infrared photoacoustic tumor imaging

Z Wang, PK Upputuri, X Zhen, R Zhang, Y Jiang, X Ai… - Nano Research, 2019 - Springer
The emerging technique of photoacoustic imaging, especially in the near infra-red (NIR)
window, permits high resolution, deep-penetration, clinically reliable sensing. However, few …

AH2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II …

J Chen, L Chen, Y Wu, Y Fang, F Zeng, S Wu… - Nature …, 2021 - nature.com
Developing high-quality NIR-II fluorophores (emission in 1000–1700 nm) for in vivo imaging
is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II …

Dynamic imaging of PEGylated indocyanine green (ICG) liposomes within the tumor microenvironment using multi-spectral optoacoustic tomography (MSOT)

N Beziere, N Lozano, A Nunes, J Salichs, D Queiros… - Biomaterials, 2015 - Elsevier
Multispectral optoacoustic tomography (MSOT) is a powerful modality that allows high-
resolution imaging of photo-absorbers deep within tissue, beyond the classical depth and …

Dual ratiometric SERS and photoacoustic core–satellite nanoprobe for quantitatively visualizing hydrogen peroxide in inflammation and cancer

Q Li, X Ge, J Ye, Z Li, L Su, Y Wu… - Angewandte Chemie …, 2021 - Wiley Online Library
Excessive production of oxidative species alters the normal redox balance and leads to
diseases, such as chronic inflammation and cancer. Oxidative species are short‐lived …