Chemically induced mouse models of acute and chronic intestinal inflammation

S Wirtz, V Popp, M Kindermann, K Gerlach… - Nature protocols, 2017 - nature.com
Inflammatory bowel diseases (IBDs) result in diarrhea and abdominal pain with further
potential complications such as tissue fibrosis and stenosis. Animal models help in …

Chemically induced mouse models of intestinal inflammation

S Wirtz, C Neufert, B Weigmann, MF Neurath - Nature protocols, 2007 - nature.com
Animal models of intestinal inflammation are indispensable for our understanding of the
pathogenesis of Crohn disease and ulcerative colitis, the two major forms of inflammatory …

Methods of inducing inflammatory bowel disease in mice

B Bang, LM Lichtenberger - Current Protocols in Pharmacology, 2016 - Wiley Online Library
Animal models of experimentally induced inflammatory bowel disease (IBD) are useful for
understanding more about the mechanistic basis of the disease, identifying new targets for …

[HTML][HTML] Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease

M Kawada, A Arihiro, E Mizoguchi - World journal of …, 2007 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), the most important being Crohn's disease and ulcerative
colitis, results from chronic dysregulation of the mucosal immune system in the …

Dextran sulfate sodium (DSS)‐induced colitis in mice

B Chassaing, JD Aitken, M Malleshappa… - Current protocols in …, 2014 - Wiley Online Library
Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis and Crohn's
Disease, are complex and multifactorial diseases with unknown etiology. For the past 20 …

Murine colitis modeling using dextran sulfate sodium (DSS)

CG Whittem, AD Williams, CS Williams - JoVE (Journal of Visualized …, 2010 - jove.com
Colitis can occur from viral or bacterial infections, ischemic insult, or autoimmune disorders;
most notably Ulcerative Colitis and the colonic variant of Crohn's Disease-Crohn's Colitis …

Investigating intestinal inflammation in DSS-induced model of IBD

JJ Kim, MS Shajib, MM Manocha, WI Khan - JoVE (Journal of Visualized …, 2012 - jove.com
Inflammatory bowel disease (IBD) encompasses a range of intestinal pathologies, the most
common of which are ulcerative colitis (UC) and Crohn's Disease (CD). Both UC and CD …

Inflammatory bowel disease: a review of pre-clinical murine models of human disease

B Katsandegwaza, W Horsnell, K Smith - International Journal of …, 2022 - mdpi.com
Crohn's disease (CD) and ulcerative colitis (UC) are both highly inflammatory diseases of
the gastrointestinal tract, collectively known as inflammatory bowel disease (IBD). Although …

Animal models of inflammatory bowel disease: lessons from enteric infections

L Eckmann - Annals of the New York Academy of Sciences, 2006 - Wiley Online Library
Mouse models of intestinal inflammation have played a key role in understanding the
mechanisms that govern the inflammatory response in the intestine, and in designing new …

Induction of TNBS colitis in mice

F Scheiffele, IJ Fuss - Current protocols in immunology, 2002 - Wiley Online Library
The animal model described in this unit is one of several that have been used to study the
immunopathogenesis of inflammatory bowel disease. The model employs the use of 2, 4, 6 …