Squalene: potential chemopreventive agent

TJ Smith - Expert opinion on investigational drugs, 2000 - Taylor & Francis
Squalene is a triterpene that is an intermediate of the cholesterol biosynthesis pathway and
it can be obtained from the diet. Olive oil contains 0.2-0.7% squalene. The average intake of …

Current insights into the biological action of squalene

JM Lou‐Bonafonte… - Molecular nutrition & …, 2018 - Wiley Online Library
Squalene is a triterpenic compound found in a large number of plants and other sources
with a long tradition of research since it was first reported in 1926. Herein a systematic …

Squalene and its potential clinical uses.

GS Kelly - Alternative medicine review: a journal of clinical …, 1999 - europepmc.org
Squalene, an isoprenoid compound structurally similar to beta-carotene, is an intermediate
metabolite in the synthesis of cholesterol. In humans, about 60 percent of dietary squalene is …

Squalene: A natural triterpene for use in disease management and therapy

LH Reddy, P Couvreur - Advanced drug delivery reviews, 2009 - Elsevier
Squalene is a natural lipid belonging to the terpenoid family and a precursor of cholesterol
biosynthesis. It is synthesized in humans and also in a wide array of organisms and …

[PDF][PDF] Medical Use of Squalene as a Natural Antioxidant.

FE Güneş - Journal of Marmara University Institute of Health …, 2013 - academia.edu
The aim of the present review is to emphasize the importance of squalene, a nutrient, in
preventive and therapeutic medicine. Squalene is a triterpene that carries oxygen …

Biological importance and applications of squalene and squalane

SK Kim, F Karadeniz - Advances in food and nutrition research, 2012 - Elsevier
Squalene is a polyunsaturated hydrocarbon with a formula of C 30 H 50. Squalene can be
found in certain fish oils, especially shark liver oil, in high amounts and some vegetable oils …

Chemopreventive effect of squalene on colon cancer.

CV Rao, HL Newmark, BS Reddy - Carcinogenesis, 1998 - academic.oup.com
Epidemiologic and laboratory studies suggest a cancer protective effect and/or lack of a
tumor promoting effect by dietary olive oil as compared with other types of non-marine oils …

Squalene, olive oil, and cancer risk: a review and hypothesis.

HL Newmark - Cancer epidemiology, biomarkers & prevention: a …, 1997 - AACR
Epidemiological studies of breast and pancreatic cancer in several Mediterranean
populations have demonstrated that increased dietary intake of olive oil is associated with a …

Squalene as novel food factor

H Narayan Bhilwade, N Tatewaki… - Current …, 2010 - ingentaconnect.com
Currently, health beneficial roles of natural products attract much attention and diverse
functional ingredients have been extensively studied their preventive effect in many …

Squalene, olive oil, and cancer risk: review and hypothesis

HL Newmark - Annals of the New York Academy of Sciences, 1999 - Wiley Online Library
Epidemiologic studies of breast and pancreatic cancer in several Mediterranean populations
have demonstrated that increased dietary intake of olive oil is associated with a small …