ESP-B4 promotes nasal epithelial cell-derived extracellular vesicles containing miR-146a-5p to modulate Smad3/GATA-3 thus relieving allergic rhinitis: ESP-B4/miR …

H Li, Y Wang, X Han - Phytomedicine, 2023 - Elsevier
Background Though generally a mild affliction, allergic rhinitis (AR) is very common and
causes considerable discomfort. Ephedra sinica polysaccharide is a candidate cost-effective …

miR‐146a enhances regulatory T‐cell differentiation and function in allergic rhinitis by targeting STAT5b

Y Zhang, Y Yang, J Guo, L Cui, L Yang, Y Li, Y Mou… - Allergy, 2022 - Wiley Online Library
Abstract Background MicroRNA (miR)‐146a, as an important immune regulatory factor with
an anti‐inflammatory effect, plays a crucial role in regulatory T‐cell (Tregs) differentiation …

Mesenchymal stem cell-derived exosome-containing Linc00632 regulates GATA binding protein-3 expression in allergic rhinitis by interacting with enhancer of zeste …

W Li, CY Cai, JJ Zeng - International Archives of Allergy and …, 2022 - karger.com
Background: Allergic rhinitis (AR) is regarded as one of the most common allergic disease of
nasal mucosa affecting many people worldwide. Long noncoding RNAs are critical …

MiR-193b-3p Regulates TLR4 Expression to Inhibit Inflammation by Targeting ETS1 in Allergic Rhinitis

YJJXM Huang, WZS Long, S Zhao - Int Arch Allergy Immunol, 2023 - karger.com
Introduction: Allergic rhinitis (AR) is identified as a multifactorial disease caused by the
interaction of genes and surroundings, which is difficult to cure. MicroRNAs were reported to …

Serum exosome-derived miR-146a-3p promotes macrophage M2 polarization in allergic rhinitis by targeting VAV3 via PI3K/AKT/mTOR pathway

C Xia, K Zhu, Y Zhang, J Chen, C Yu, T Gao… - International …, 2023 - Elsevier
Background Our previous study showed that miR-146a-3p was elevated in serum exosomes
of allergic rhinitis (AR) patients, but the underlying mechanisms were unclarified. This study …

[HTML][HTML] Xiao-qing-long-tang ameliorates OVA-induced allergic rhinitis by inhibiting ILC2s through the IL-33/ST2 and JAK/STAT pathways

J Zhang, X He, M Zhou, Q Liu, W Xu, Y Yan, Y Ruan - Phytomedicine, 2023 - Elsevier
Background Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa that
is mediated by immunoglobulin E (IgE). Xiao-qing-long-tang (XQLT) is a traditional Chinese …

[HTML][HTML] Increased miR-124-3p alleviates type 2 inflammatory response in allergic rhinitis via IL-4Rα

Q Liu, Y Shen, Y Xiao, H Xiang, L Chu, T Wang… - Inflammation …, 2022 - Springer
Background and objectives miRNAs play a crucial role in regulating immune responses.
However, the effect of miR-124-3p on type 2 inflammation in allergic rhinitis (AR) is unclear …

MiR-146a mimic attenuates murine allergic rhinitis by downregulating TLR4/TRAF6/NF-κB pathway

J Wang, Z Cui, L Liu, S Zhang, Y Zhang, Y Zhang… - …, 2019 - Taylor & Francis
Aim: This study aims to investigate whether microRNA (miR)-146a exerts therapeutic
potential to allergic rhinitis (AR). Methods: Female BALB/c mice were randomly divided into …

HMSC‐derived exosome inhibited Th2 cell differentiation via regulating miR‐146a‐5p/SERPINB2 pathway

J Zhou, Y Lu, W Wu, Y Feng - Journal of Immunology Research, 2021 - Wiley Online Library
Background. Allergic rhinitis (AR) is a global disease without specific treatment. Human
mesenchymal stem cell‐(HMSC‐) derived exosomes (HMSC‐exos) have been implicated …

Astragalus polysaccharide relieves inflammatory responses in guinea pigs with allergic rhinitis via ameliorating NF-kB-mediated Treg/Th17 imbalance

X He, L Liu, X Luo, J Zhu, H Yang… - American Journal of …, 2022 - journals.sagepub.com
Background Allergic rhinitis (AR) is regarded as a prevalent and non-infectious inflammation
in nasal mucosa, and astragalus polysaccharide (APS) could mitigate inflammation …