Multi-targeted immunotherapeutics to treat B cell malignancies
The concept of multi-targeted immunotherapeutic systems has propelled the field of cancer
immunotherapy into an exciting new era. Multi-effector molecules can be designed to …
immunotherapy into an exciting new era. Multi-effector molecules can be designed to …
Review of bi-specific therapies in uveal melanoma
M Orloff, R Seedor, T Sato - Cancer Gene Therapy, 2022 - nature.com
Uveal melanoma is a rare subtype of melanoma that once metastatic portends a poor
prognosis. Likely due to the distinct differences in biology, metastatic potential, and …
prognosis. Likely due to the distinct differences in biology, metastatic potential, and …
Antibody-based therapeutics for the treatment of human B cell malignancies
S Baskar, N Muthusamy - Current allergy and asthma reports, 2013 - Springer
The dynamic expression of various phenotypic markers during B cell development not only
defines the particular stage in ontogeny but also provides the necessary growth …
defines the particular stage in ontogeny but also provides the necessary growth …
Education and empowering special forces to eradicate secret defectors: immune system-based treatment approaches for mature T-and NK-cell Malignancies
T Braun, A Schrader - Cancers, 2023 - mdpi.com
Simple Summary Mature T-and NK-cell leukemia/lymphoma (MTCL/L) are a heterogeneous
group of rare, mostly poor prognostic neoplastic entities. In the past, immunotherapeutic …
group of rare, mostly poor prognostic neoplastic entities. In the past, immunotherapeutic …
Immunotherapy for uveal melanoma
MP Breazzano, RW Milam Jr, SA Batson… - International …, 2017 - journals.lww.com
Uveal melanoma is the most common primary intraocular tumor in adults. 1 Before the mid-
20th century, enucleation was the mainstay of treatment for uveal melanoma. Although this …
20th century, enucleation was the mainstay of treatment for uveal melanoma. Although this …
[引用][C] Dual immunological checkpoint blockade for uveal melanoma
S Khan, RD Carvajal - Journal of Clinical Oncology, 2021 - ascopubs.org
Despite the dramatic progress that has been made in elucidating the complex biology of
cancer and translating this knowledge into novel therapeutics, there remain malignancies for …
cancer and translating this knowledge into novel therapeutics, there remain malignancies for …
Immunotherapy in uveal melanoma: novel strategies and opportunities for personalized treatment
C Masaoutis, S Kokkali… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Uveal melanoma (UM) is the most common intraocular cancer and represents a
discrete subtype of melanoma. Metastatic disease, which occurs in half of patients, has a …
discrete subtype of melanoma. Metastatic disease, which occurs in half of patients, has a …
Immune checkpoint inhibitors in uveal and conjunctival melanoma
APA Wierenga, J Cao, GPM Luyten… - International …, 2019 - journals.lww.com
Many therapies are being developed that use the patient's own immune response to treat
malignancies. One of the new types of immunotherapy is the application of monoclonal …
malignancies. One of the new types of immunotherapy is the application of monoclonal …
The role of immune checkpoint blockade in uveal melanoma
A Wessely, T Steeb, M Erdmann, L Heinzerling… - International journal of …, 2020 - mdpi.com
Uveal melanoma (UM) represents the most common intraocular malignancy in adults and
accounts for about 5% of all melanomas. Primary disease can be effectively controlled by …
accounts for about 5% of all melanomas. Primary disease can be effectively controlled by …
Targeted biological drugs and immune check point inhibitors for locally advanced or metastatic cancers of the conjunctiva, eyelid, and orbit
B Esmaeli, O Sagiv - International Ophthalmology Clinics, 2019 - journals.lww.com
Surgery remains the mainstay treatment for the majority of carcinomas and melanomas in
the periocular region, orbit, and conjunctiva. However, for patients with locally advanced or …
the periocular region, orbit, and conjunctiva. However, for patients with locally advanced or …