Despite improvements in diagnosis, intensive-care medicine and surgical technique, the
mortality of patients with secondary peritonitis is still high. Early and aggressive empiric …

Background Acute postoperative peritonitis resulting from previous abdominal surgery is still
a severe and potentially fatal disease, which is associated with high morbidity and mortality …

Adequate management of severely ill patients with secondary peritonitis requires supportive
therapy of organ dysfunction, source control of infection and antimicrobial therapy. Since …

This study aims to determine whether abdominal microbial profiles in early severe
secondary peritonitis are associated with ongoing infection or death. The study is performed …

Background: Selecting an appropriate agent for empiric antibiotic therapy for secondary
peritonitis is challenging. The pathogens responsible, aerobic gram-negative bacilli in …

Background Secondary peritonitis requires surgical source control and adequate
antimicrobial treatment. Antimicrobial regimens are usually selected according to local …

Objective. Spontaneous bacterial peritonitis is a common infection in cirrhosis, associated
with a high mortality. Third-generation cephalosporins are recommended as first-line …

Background Temporal changes in the microbiological resistance profile have been reported
in several life-threatening infections. However, no data have ever assessed this issue in …

Background: In patients with intra-abdominal infection, inappropriate initial empiric antibiotic
therapy is associated with greater morbidity. We evaluated the impact of adequate empiric …

Background: Critically ill surgical patients remain at a high risk of adverse outcomes as a
result of secondary peritonitis (SP). The risk is even higher if tertiary peritonitis (TP) …