Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Spinal cord injury and related clinical trials

YH Kim, KY Ha, SI Kim - Clinics in orthopedic surgery, 2017 - synapse.koreamed.org
Spinal cord injury (SCI) has been considered an incurable condition and it often causes
devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage …

Recent progress and challenges in the treatment of spinal cord injury

T Tian, S Zhang, M Yang - Protein & cell, 2023 - academic.oup.com
Spinal cord injury (SCI) disrupts the structural and functional connectivity between the higher
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …

Emerging repair, regeneration, and translational research advances for spinal cord injury

BK Kwon, LH Sekhon, MG Fehlings - Spine, 2010 - journals.lww.com
Study Design. Literature review of basic scientific and clinical research in spinal cord injury
(SCI). Objective. To provide physicians with an overview of the neurobiologic challenges of …

Pathophysiology of spinal cord injury

LD Hachem, MG Fehlings - Neurosurgery Clinics, 2021 - neurosurgery.theclinics.com
Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Delving into the recent advancements of spinal cord injury treatment: a review of recent progress

JA Flack, KD Sharma, JY Xie - Neural regeneration research, 2022 - journals.lww.com
Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI
literatures can be beneficial to current and future researchers. This review focuses on recent …

[HTML][HTML] Cellular treatments for spinal cord injury: the time is right for clinical trials

MG Fehlings, R Vawda - Neurotherapeutics, 2011 - Elsevier
More than 1 million people in the United States live with a spinal cord injury (SCI). Despite
medical advances, many patients with SCIs still experience substantial neurological …

[HTML][HTML] Current advancements in the management of spinal cord injury: A comprehensive review of literature

M Shah, C Peterson, E Yilmaz… - Surgical neurology …, 2020 - ncbi.nlm.nih.gov
Background: Spinal cord injury (SCI) carries debilitating lifelong consequences and,
therefore, requires careful review of different treatment strategies. Methods: An extensive …