Across neurodegenerative diseases, common mechanisms may reveal novel therapeutic
targets based on neuronal protection, repair, or regeneration, independent of etiology or site …

Glaucoma is the principal cause of irreversible blindness in the world. The disease leads to
progressive optic nerve degeneration with a gradual loss of retinal ganglion cells …

Divergent disease triggers in neurodegeneration may induce convergent endogenous
pathways in neuronal, glial and vascular elements as the central nervous system (CNS) …

Glaucoma is a chronic neurodegenerative disease characterized by apoptosis of retinal
ganglion cell (RGC) somas, degeneration of axons, and loss of synapses at dendrites and …

Glaucoma is the most common age-related optic nerve disease and also the most common
neuropathy, affecting∼ 60 million people worldwide in its most common forms. This figure is …

Glaucoma is a common, complex, multifactorial neurodegenerative disease characterized
by progressive dysfunction and then loss of retinal ganglion cells, the output neurons of the …

Neurodegenerative diseases are among the leading causes of disability and death
worldwide. The disease-related socioeconomic burden is expected to increase with the …

Glaucoma is a progressive neurodegenerative disease of retinal ganglion cells (RGCs)
associated with characteristic axon degeneration in the optic nerve. Clinically, our only …

Developing therapies for neurodegenerative diseases will require new scientific approaches
that take into account the detrimental effects of altered protein and RNA homeostasis on …

The human body is highly complex and comprises a variety of living cells and extracellular
material, which forms tissues, organs, and organ systems. Human cells tend to turn over …