[HTML][HTML] Lead exposure and (n-3) fatty acid deficiency during rat neonatal development affect subsequent spatial task performance and olfactory discrimination

SY Lim, JD Doherty, K McBride, NJ Miller-Ihli… - The Journal of …, 2005 - Elsevier
ABSTRACT Docosahexaenoic acid [22: 6 (n-3), DHA] is important for optimal infant central
nervous system development, and lead (Pb) exposure during development can produce …

[HTML][HTML] Lead exposure and (n-3) fatty acid deficiency during rat neonatal development alter liver, plasma, and brain polyunsaturated fatty acid composition

SY Lim, JD Doherty, N Salem Jr - The Journal of nutrition, 2005 - Elsevier
Lead (Pb) exposure has been reported to increase arachidonic (AA) and docosahexaenoic
(DHA) acids. To determine whether Pb effects on fatty acid composition are influenced by …

[HTML][HTML] Dietary (n-3) fatty acids and brain development1

SM Innis - The Journal of nutrition, 2007 - Elsevier
Abstract The (n-3) fatty acids are essential dietary nutrients, and one of their important roles
is providing docosahexaenoic acid [22: 6 (n-3)](DHA) for growth and function of nervous …

Developmental effects of dietary n− 3 fatty acids on activity and response to novelty

B Levant, TJ Zarcone, SC Fowler - Physiology & behavior, 2010 - Elsevier
Insufficient availability of n− 3 polyunsaturated fatty acids (PUFA) during pre-and neonatal
development decreases accretion of docosahexaenoic acid (DHA, 22: 6n− 3) in the …

N-3 fatty acid deficiency induced by a modified artificial rearing method leads to poorer performance in spatial learning tasks

SY Lim, J Hoshiba, T Moriguchi, N Salem - Pediatric research, 2005 - nature.com
Docosahexaenoic acid (DHA) is a major structural component of the nervous system, and
depletion may lead to losses in neural function. Our objective was to demonstrate a deficit in …

[HTML][HTML] Perinatal brain docosahexaenoic acid concentration has a lasting impact on cognition in mice

LE Lozada, A Desai, K Kevala, JW Lee, HY Kim - The Journal of Nutrition, 2017 - Elsevier
Background Premature infants are deprived of prenatal accumulation of brain
docosahexaenoic acid [DHA (22: 6n-3)], an omega-3 fatty acid [ω-3 FA (n-3 FA)] important …

Prenatal docosahexaenoic acid supplementation has long-term effects on childhood behavioral and brain responses during performance on an inhibitory task …

KM Gustafson, K Liao, NB Mathis… - Nutritional …, 2022 - Taylor & Francis
Introduction: Offsprings from a prenatal docosahexaenoic acid (DHA) supplementation trial,
in which pregnant women were assigned to placebo or 600mg DHA/day, were followed to …

Olfactory discrimination deficits in n− 3 fatty acid-deficient rats

RS Greiner, T Moriguchi, BM Slotnick, A Hutton… - Physiology & …, 2001 - Elsevier
Docosahexaenoic acid (DHA), a long chain n− 3 fatty acid, is present in high concentrations
in the central nervous system. Although the role that DHA may play in neural function is not …

Maternal dietary docosahexanoic acid content affects the rat pup auditory system

LY Haubner, JE Stockard, MD Saste, VJ Benford… - Brain research …, 2002 - Elsevier
Previous studies of the effects of dietary docosahexanoic acid (DHA), 22: 6n3, on
neurodevelopment have focused mainly on visual-evoked potentials and indices of visual …

Dietary essential fatty acids and brain function: a developmental perspective on mechanisms

PE Wainwright - Proceedings of the Nutrition Society, 2002 - cambridge.org
Brain development is a complex interactive process in which early disruptive events can
have long-lasting effects on later functional adaptation. It is a process that is dependent on …