Modified Zhenwu Tang delays chronic renal failure progression by modulating oxidative stress and hypoxic responses in renal proximal tubular epithelial cells
Y Zhang, P Jin, D Guo, D Bian - Heliyon, 2024 - cell.com
Background Tubulointerstitial fibrosis (TIF) is a critical pathological feature of chronic renal
failure (CRF), with oxidative stress (OS) and hypoxic responses in renal proximal tubular …
failure (CRF), with oxidative stress (OS) and hypoxic responses in renal proximal tubular …
[HTML][HTML] Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating …
J Wang, X Guo, Z Zou, M Yu, X Li, H Xu, Y Chen… - Biomedicine & …, 2023 - Elsevier
Renal interstitial fibrosis (RIF), a progressive process affecting the kidneys in chronic kidney
disease (CKD), currently lacks an effective therapeutic intervention. Traditional Chinese …
disease (CKD), currently lacks an effective therapeutic intervention. Traditional Chinese …
Thiobarbiturate-Derived Compound MHY1025 Alleviates Renal Fibrosis by Modulating Oxidative Stress, Epithelial Inflammation, and Fibroblast Activation
Chronic kidney disease (CKD) is a kidney structure and function abnormality. CKD
development and progression are strongly influenced by oxidative stress and inflammatory …
development and progression are strongly influenced by oxidative stress and inflammatory …
Wen-pi-tang-Hab-Wu-ling-san reduces ureteral obstructive renal fibrosis by the reduction of oxidative stress, inflammation, and TGF-β/Smad2/3 signaling
Kidney fibrosis results in chronic renal disease. The current treatment of chronic renal
diseases is limited to angiotensin converting enzyme inhibitors and angiotensin receptor …
diseases is limited to angiotensin converting enzyme inhibitors and angiotensin receptor …
Combination of active components of Xiexin decoction ameliorates renal fibrosis through the inhibition of NF-κB and TGF-β1/Smad pathways in db/db diabetic mice
JS Wu, R Shi, X Lu, YM Ma, NN Cheng - PloS one, 2015 - journals.plos.org
Xiexin decoction, a herbal therapeutic agent commonly used in traditional Chinese
medicine, is recognized for its beneficial effects on diabetic nephropathy exerted through the …
medicine, is recognized for its beneficial effects on diabetic nephropathy exerted through the …
[HTML][HTML] The flavonoid fisetin ameliorates renal fibrosis by inhibiting SMAD3 phosphorylation, oxidative damage, and inflammation in ureteral obstructed kidney in …
HY Ju, J Kim, SJ Han - Kidney Research and Clinical Practice, 2023 - ncbi.nlm.nih.gov
Background Renal fibrosis is characterized by the accumulation of extracellular matrix and
inflammatory cells and kidney dysfunction, which is a major pathway in the progression of …
inflammatory cells and kidney dysfunction, which is a major pathway in the progression of …
Network Pharmacology and In Vivo Analysis of Dahuang‐Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis
Y Luo, C Xuan, J Cheng, Y Xiong… - … and Alternative Medicine, 2022 - Wiley Online Library
Dahuang and Huangqi are the most frequently prescribed treatment methods for chronic
kidney disease in China. Our study aimed to clarify the pharmacological mechanism of …
kidney disease in China. Our study aimed to clarify the pharmacological mechanism of …
Yishen Huoxue decoction (益肾活血方) attenuates unilateral ureteric obstruction-induced renal fibrosis and hypoxia-induced reactive oxygen species generation via …
Z Jian, F Guiyu, W Zixia, C Ping… - Journal of …, 2021 - search.ebscohost.com
OBJECTIVE: To investigate the effeicacy of Yishen Huoxue decoction (YSHX) on renal
fibrosis induced by unilateral ureteric obstruction (UUO), and on reactive oxygen species …
fibrosis induced by unilateral ureteric obstruction (UUO), and on reactive oxygen species …
Recombinant long-acting thioredoxin ameliorates AKI to CKD transition via modulating renal oxidative stress and inflammation
K Nishida, H Watanabe, R Murata, K Tokumaru… - International Journal of …, 2021 - mdpi.com
An effective strategy is highly desirable for preventing acute kidney injury (AKI) to chronic
kidney disease (CKD) transition. Thioredoxin-1 (Trx), a redox-active protein that has anti …
kidney disease (CKD) transition. Thioredoxin-1 (Trx), a redox-active protein that has anti …
Protection effect of Zhen‐Wu‐tang on adriamycin‐induced nephrotic syndrome via inhibiting oxidative lesions and inflammation damage
C Liang, J Wu, J Lai, S Ye, J Lin… - Evidence‐Based …, 2014 - Wiley Online Library
Zhen‐wu‐tang (ZWT), a well‐known formula in China, is widely used to treat chronic kidney
diseases. However, very little information on ZWT's mechanism of action is currently …
diseases. However, very little information on ZWT's mechanism of action is currently …
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