Overexpression of TRPM2 Channels by Oxidative Stress-Mediated Reperfusion Injury.
F BALGETİR, T KULOĞLU, S BULUT… - … Sağlik Bilimleri Tip …, 2022 - search.ebscohost.com
Objective: Since it can be activated by oxidative stress, the TRP melastatin 2 (TRPM2)
channel has recently been established as a potential therapeutic target in the fight against …
channel has recently been established as a potential therapeutic target in the fight against …
[HTML][HTML] Oksidatif Stres İlişkili Reperfüzyon Hasarı ile TRPM2 Kanallarının Aşırı Ekspresyonu
Amaç: TRP melastatin 2 (TRPM2) kanalı oksidatif stres tarafından aktive edilebildiğinden
diyabet, inflamasyon, miyokard enfarktüsü gibi oksidatif strese bağlı hastalıklarla …
diyabet, inflamasyon, miyokard enfarktüsü gibi oksidatif strese bağlı hastalıklarla …
Abstract TP286: The Study of the Role and Mechanism of TRPM7 in Acute Cerebral Ischemia-Reperfusion Injury
J Xu, L Chen, L Zeng, C Li, X Yang, J Zhang, S Wang… - Stroke, 2020 - Am Heart Assoc
Although the NMDA receptor was identified to mediate excitotoxicity for ischemia-
reperfusion (IR) injury, its antagonists have not shown clinical efficacy. Unrelated to NMDA …
reperfusion (IR) injury, its antagonists have not shown clinical efficacy. Unrelated to NMDA …
A critical review on TRPM2 channel expression increase-induced induces neuronal cell death and oxidative stress.
A DEMİR - Journal of Cellular Neuroscience & Oxidative …, 2024 - search.ebscohost.com
It has long been recognized that voltage-gated calcium and chemical channels influence the
Ca< sup> 2+ influx in neural cells. Transient receptor potential, or TRP, is a novel channel …
Ca< sup> 2+ influx in neural cells. Transient receptor potential, or TRP, is a novel channel …
TRPM4 activation by chemically-and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death
E Leiva-Salcedo, D Riquelme, O Cerda, A Stutzin - Channels, 2017 - Taylor & Francis
Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal
death. This process has two components, a glutamate-dependent and a glutamate …
death. This process has two components, a glutamate-dependent and a glutamate …
[HTML][HTML] Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injury
K Zhan, P Yu, C Liu, J Luo, W Yang - Acta Pharmacologica Sinica, 2016 - nature.com
Abstract Ischemia/reperfusion (I/R) injury is the main cause of tissue damage and
dysfunction. I/R injury is characterized by Ca 2+ overload and production of reactive oxygen …
dysfunction. I/R injury is characterized by Ca 2+ overload and production of reactive oxygen …
[PDF][PDF] The effects of TRPM2, TRPM6, TRPM7 and TRPM8 gene expression in hepatic ischemia reperfusion injury.
OBJECTIVE: Mammalian transient receptor potential melastatin (TRPM) channels are a form
of calcium channels and they transport calcium and magnesium ions. TRPM has eight …
of calcium channels and they transport calcium and magnesium ions. TRPM has eight …
Expressions of TRPM6 and TRPM7 and histopathological evaluation of tissues in ischemia reperfusion performed rats
R Dokuyucu, B Gogebakan, O Yumrutas, I Bozgeyik… - Renal failure, 2014 - Taylor & Francis
There is very little work on the expression of TRPM6/7 in ischemia reperfusion models. In
previous studies, after ischemia, reperfusion had been kept limited to 24 h, yet in our study …
previous studies, after ischemia, reperfusion had been kept limited to 24 h, yet in our study …
[引用][C] A primary study of TRPM2 on SH-SY5Y cell injury after OGD/R
X Li, F Yu, D Huang - Journal of the Neurological Sciences, 2021 - jns-journal.com
Methods SH-SY5Y cells were subjected to oxygen-glucose deprivation/reperfusion (OGD/R)
to mimic cerebral I/R injury in vitro. Cell morphology, viability and apoptosis were detected …
to mimic cerebral I/R injury in vitro. Cell morphology, viability and apoptosis were detected …
[HTML][HTML] The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia
E Turlova, Z Feng, H Sun - Acta Pharmacologica Sinica, 2018 - nature.com
Stroke is one of the major causes of mortality and morbidity worldwide, yet novel therapeutic
treatments for this condition are lacking. This review focuses on the roles of the transient …
treatments for this condition are lacking. This review focuses on the roles of the transient …