Cardiopulmonary bypass and edema: physiology and pathophysiology

E Hirleman, DF Larson - Perfusion, 2008 - journals.sagepub.com
Edema is a common morbidity following cardiopulmonary bypass (CPB) and can result in
injury to many organs, including the heart, lungs, and brain. Generalized edema is also …

Pathophysiology of cardiopulmonary bypass: current strategies for the prevention and treatment of anemia, coagulopathy, and organ dysfunction

SA Esper, K Subramaniam… - … in cardiothoracic and …, 2014 - journals.sagepub.com
The techniques and equipment of cardiopulmonary bypass (CPB) have evolved over the
past 60 years, and numerous numbers of cardiac surgical procedures are conducted around …

Early postoperative fluid overload precedes acute kidney injury and is associated with higher morbidity in pediatric cardiac surgery patients

AB Hassinger, EL Wald… - Pediatric Critical Care …, 2014 - journals.lww.com
Objective: Fluid overload has been independently associated with increased morbidity and
mortality in pediatric patients with renal failure, acute lung injury, and sepsis. Pediatric …

Renal and cerebral hypoxia and inflammation during cardiopulmonary bypass

AH Jufar, YR Lankadeva, CN May… - Comprehensive …, 2011 - Wiley Online Library
Cardiac surgery‐associated acute kidney injury and brain injury remain common despite
ongoing efforts to improve both the equipment and procedures deployed during …

Highly positive intraoperative fluid balance during cardiac surgery is associated with adverse outcome

F Toraman, S Evrenkaya, M Yuce, O Turek… - …, 2004 - journals.sagepub.com
Hemodilution and increase in capillary permeability occurring with cardiopulmonary bypass
(CPB) impose a risk for tissue edema and blood transfusion that may result in an increased …

Early prediction of capillary leak syndrome in infants after cardiopulmonary bypass

R Kubicki, J Grohmann, M Siepe, C Benk… - European Journal of …, 2013 - academic.oup.com
OBJECTIVES As an inflammatory reaction after cardiac surgery involving cardiopulmonary
bypass (CPB), capillary leak syndrome (CLS) is associated with increased morbidity …

Myocardial fluid balance

U Mehlhorn, HJ Geissler, GA Laine… - European journal of …, 2001 - academic.oup.com
Fluid accumulation in the cardiac interstitium or myocardial edema is a common
manifestation of many clinical states. Specifically, cardiac surgery includes various …

Dynamic evaluation of fluid shifts during normothermic and hypothermic cardiopulmonary bypass in piglets

JK Heltne, ME Koller, T Lund, J Bert… - Acta …, 2000 - Wiley Online Library
Background: Edema, generalized overhydration and organ dysfunction commonly occur in
patients undergoing open‐heart surgery using cardiopulmonary bypass (CPB) and induced …

Fluid overload is associated with higher mortality and morbidity in pediatric patients undergoing cardiac surgery

DJ Lex, R Tóth, NR Czobor, SI Alexander… - Pediatric Critical Care …, 2016 - journals.lww.com
Objectives: Fluid overload after pediatric cardiac surgery is common and has been shown to
increase both mortality and morbidity. This study explores the risk factors of early …

Increasing the colloid osmotic pressure of cardiopulmonary bypass prime and normothermic blood cardioplegia minimizes myocardial oedema and prevents cardiac …

U Mehlhorn, SJ Allen, KL Davis, HJ Geissler… - Cardiovascular …, 1998 - Elsevier
Our recent work demonstrated that normothermic continuous antegrade blood cardioplegia
results in cardiac dysfunction related to myocardial oedema. This oedema was partially due …