Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA
composition of EVs is challenging due to their coisolation with contaminants, lack of …
composition of EVs is challenging due to their coisolation with contaminants, lack of …
Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes
OA Kossinova, AV Gopanenko, SN Tamkovich… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Exosomes, membranous vesicles secreted by various cells, are involved in intercellular
communication and carry vast repertoires of RNAs and proteins. Processes mediating RNA …
communication and carry vast repertoires of RNAs and proteins. Processes mediating RNA …
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
MJ Shurtleff, MM Temoche-Diaz, KV Karfilis, S Ri… - elife, 2016 - elifesciences.org
Exosomes are small vesicles that are secreted from metazoan cells and may convey
selected membrane proteins and small RNAs to target cells for the control of cell migration …
selected membrane proteins and small RNAs to target cells for the control of cell migration …
[HTML][HTML] Reassessment of exosome composition
The heterogeneity of small extracellular vesicles and presence of non-vesicular extracellular
matter have led to debate about contents and functional properties of exosomes. Here, we …
matter have led to debate about contents and functional properties of exosomes. Here, we …
Exosomes secreted by human cells transport largely mRNA fragments that are enriched in the 3′-untranslated regions
AO Batagov, IV Kurochkin - Biology direct, 2013 - Springer
Small secreted membrane vesicles called exosomes have recently attracted a great interest
after the discovery that they transfer mRNA that can be translated into protein in recipient …
after the discovery that they transfer mRNA that can be translated into protein in recipient …
Isolation and characterization of RNA-containing exosomes
C Lässer, M Eldh, J Lötvall - JoVE (Journal of Visualized Experiments), 2012 - jove.com
The field of exosome research is rapidly expanding, with a dramatic increase in publications
in recent years. These small vesicles (30-100 nm) of endocytic origin were first proposed to …
in recent years. These small vesicles (30-100 nm) of endocytic origin were first proposed to …
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
C Villarroya-Beltri, C Gutiérrez-Vázquez… - Nature …, 2013 - nature.com
Exosomes are released by most cells to the extracellular environment and are involved in
cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs …
cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs …
Identification of RNA-binding proteins in exosomes capable of interacting with different types of RNA: RBP-facilitated transport of RNAs into exosomes
L Statello, M Maugeri, E Garre, M Nawaz, J Wahlgren… - PloS one, 2018 - journals.plos.org
The RNA that is packaged into exosomes is termed as exosomal-shuttle RNA (esRNA);
however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely …
however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely …
Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
Exosomes may mediate cell-to-cell communication by transporting various proteins and
nucleic acids to neighboring cells. Some protein and RNA cargoes are significantly enriched …
nucleic acids to neighboring cells. Some protein and RNA cargoes are significantly enriched …
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …