[HTML][HTML] Gene Duplication Associated with Increased Fluconazole Tolerance in Candida auris cells of Advanced Generational Age
S Bhattacharya, T Holowka, EP Orner, BC Fries - Scientific reports, 2019 - nature.com
Candida auris is an emerging multi-drug resistant yeast that causes systemic infections.
Here we show that C. auris undergoes replicative aging (RA) that results from asymmetric …
Here we show that C. auris undergoes replicative aging (RA) that results from asymmetric …
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris
J Bing, T Hu, Q Zheng, JF Muñoz… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Candida auris is a newly emerging fungal pathogen of humans and has attracted
considerable attention from both the clinical and basic research communities. Clinical …
considerable attention from both the clinical and basic research communities. Clinical …
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance
Candida auris is an emerging fungal pathogen and a serious global health threat as the
majority of clinical isolates display elevated resistance to currently available antifungal …
majority of clinical isolates display elevated resistance to currently available antifungal …
Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo
Antifungal drug resistance and tolerance pose a serious threat to global public health. In the
human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin …
human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin …
Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …
A zinc cluster transcription factor contributes to the intrinsic fluconazole resistance of Candida auris
EM Mayr, B Ramírez-Zavala, I Krüger, J Morschhäuser - Msphere, 2020 - Am Soc Microbiol
The recently emerged pathogenic yeast Candida auris is a major concern for human health,
because it is easily transmissible, difficult to eradicate from hospitals, and highly drug …
because it is easily transmissible, difficult to eradicate from hospitals, and highly drug …
Deciphering the Mrr1/Mdr1 pathway in azole resistance of Candida auris
Candida auris is an emerging yeast pathogen with a remarkable ability to develop antifungal
resistance, in particular to fluconazole and other azoles. Azole resistance in C. auris was …
resistance, in particular to fluconazole and other azoles. Azole resistance in C. auris was …
Upc2-mediated mechanisms of azole resistance in Candida auris
J Li, L Aubry, D Brandalise, AT Coste… - Microbiology …, 2024 - Am Soc Microbiol
Candida auris is an emerging yeast pathogen of major concern because of its ability to
cause hospital outbreaks of invasive candidiasis and to develop resistance to antifungal …
cause hospital outbreaks of invasive candidiasis and to develop resistance to antifungal …
[HTML][HTML] Candida auris Genetics and Emergence
A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
Directed evolution detects supernumerary centric chromosomes conferring resistance to azoles in Candida auris
Candida auris exhibits resistance to multiple antifungal drug classes and sterilization
agents, posing threats to the immunocompromised worldwide. Among the four major …
agents, posing threats to the immunocompromised worldwide. Among the four major …
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