Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …

Malaria during pregnancy is a major health problem for African women. The disease is
caused by Plasmodium falciparum malaria parasites, which accumulate in the placenta by …

In high‐transmission regions, protective clinical immunity to Plasmodium falciparum
develops during the early years of life, limiting serious complications of malaria in young …

Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

Pregnancy-associated malaria is caused by Plasmodium falciparum malaria parasites
binding specifically to chondroitin sulfate A in the placenta. This sequestration of parasites is …

Plasmodium falciparum parasites that bind to chondroitin sulphate A (CSA) express unique
variant surface antigens that are involved in the placental sequestration that precipitates …

Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

Infection with Plasmodium falciparum during pregnancy is one of the major causes of
malaria related morbidity and mortality in newborn and mothers. The complications of …

Background. Binding to chondroitin sulfate A by VAR2CSA, a parasite protein expressed on
infected erythrocytes, allows placental sequestration of Plasmodium falciparum–infected …