Several agents used for treatment of colon and other cancers induce reactive oxygen
species (ROS), and this plays an important role in their anticancer activities. In addition to …

Simple Summary Colorectal cancer is a disease associated with a high mortality rate. During
the tumorigenic process, several factors and signaling molecules produced by tumor cells …

Colorectal cancer (CRC) has become the fourth leading cause of cancer‐related death in
the worldwide. It is urgent to find more effective therapeutic strategies for it. Reactive oxygen …

Reactive oxygen species (ROS) are produced by mitochondria during metabolism. In
physiological states, the production of ROS and their elimination by antioxidants are kept in …

Background/Aims: Elevated oxidative status has been found in many types of cancer cells.
Recent studies have shown that the enzymatic product of thymidine phosphorylase (TP) …

Cells are continuously threatened by the damage caused by reactive oxygen/nitrogen
species (ROS/RNS), which are produced during physiological oxygen metabolism. In our …

Reactive oxygen species (ROS) are molecules or ions formed by the incomplete one-
electron reduction of oxygen. Of interest, it seems that ROS manifest dual roles, cancer …

Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …

Simple Summary Colorectal cancer (CRC) is very common throughout the world. Despite an
improved outcome with the current treatment regimen, a huge number of patients relapse …

Oxaliplatin-based chemotherapy is recommended as the first-line therapeutic regimen for
metastatic colorectal cancer. However, long-term and repeated oxaliplatin therapy leads to …