Breast cancer is a principal cause of cancer-related mortality in female worldwide. While
many approved therapies have shown promising outcomes in treating breast cancer …

Breast cancer is the most common cancer type amongst women, accounting for most female
cancer deaths second to cervical cancer worldwide. It is, therefore, highly crucial to …

An enormous body of literature has accumulated over the past 15 years implicating
apoptosis (programmed cell death) in breast cancer cell death induced by conventional and …

Breast carcinoma represents the second leading cause of cancer death in developed
countries amongst women. Current cytotoxic chemotherapy plays an important role in the …

A critical first step in the personalized approach to cancer treatment is the identification of
activated oncogenes that drive each tumor. The Identification of driver oncogenes on a …

Targeted chemotherapy has become the forefront for cancer treatment in recent years. The
selective and specific features allow more effective treatment with reduced side effects. Most …

Breast cancer arises from the malignant transformation of mammary epithelial cells under
the influence of various carcinogenic factors, leading to a gradual increase in its prevalence …

Targeting apoptosis for the treatment of cancer has become an increasingly attractive
strategy, with agents in development to trigger extrinsic apoptosis via TRAIL signalling, or to …

Treatment approaches for cancer, for example chemotherapy, radiotherapy, or
immunotherapy, primarily act by inducing cell death in cancer cells. Consequently, the …

Programmed cell death or apoptosis is of fundamental importance to cancer as it both limits
tumorigenesis and is also triggered by many cancer chemotherapeutics. Many oncogenes …