[HTML][HTML] Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and …

J Gu, A Kong, C Guo, J Liu, K Li, Z Ren, Y Zhou… - Ecotoxicology and …, 2022 - Elsevier
Abstract Cadmium ion (Cd 2+) exposure has been reported to associate with the prevalence
of dyslipidemia, and contribute to the initiation and progression of nonalcoholic fatty liver …

Effects of chronic cadmium exposure at food limitation-relevant levels on energy metabolism in mice

X He, Z Qi, H Hou, J Gao, XX Zhang - Journal of hazardous materials, 2020 - Elsevier
Cadmium (Cd) exposure has been implicated in the perturbation of energy metabolism and
the development of cardiometabolic disease, but disease predisposition from chronic low …

Inhibition of mitochondrial fatty acid oxidation contributes to development of nonalcoholic fatty liver disease induced by environmental cadmium exposure

X He, J Gao, H Hou, Z Qi, H Chen… - Environmental science & …, 2019 - ACS Publications
Cadmium (Cd) is one of the most prevalent toxic metal pollutants widely distributed in water
and soil environments. Epidemiological studies have shown that exposure to Cd is …

[HTML][HTML] Chronic exposure to low-dose cadmium facilitated nonalcoholic steatohepatitis in mice by suppressing fatty acid desaturation

Y Zhu, Y Zhao, XX Chai, J Zhou, MJ Shi, Y Zhao… - Ecotoxicology and …, 2022 - Elsevier
Exposure to cadmium (Cd), a toxic metal, is epidemiologically linked to nonalcoholic
steatohepatitis (NASH) in humans. However, the role of Cd in NASH remains to be fully …

[HTML][HTML] Synergistic hepatotoxicity by cadmium and chlorpyrifos: disordered hepatic lipid homeostasis

W He, W Guo, Y Qian, S Zhang… - Molecular medicine …, 2015 - spandidos-publications.com
Due to its extensive application, chlorpyrifos (CPF) has contaminated a diverse range of
environmental substrates, fruits and vegetables. A number of studies have suggested that …

Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice

J Zhang, Y Wang, L Fu, YJ Feng, YL Ji… - Journal of Applied …, 2018 - Wiley Online Library
Cadmium (Cd) is a persistent environmental and occupational contaminant that
accumulates in humans and shows adverse effects on health. Accumulating evidence …

Low-dose cadmium causes metabolic and genetic dysregulation associated with fatty liver disease in mice

YM Go, RL Sutliff, JD Chandler, R Khalidur… - Toxicological …, 2015 - academic.oup.com
Cadmium (Cd) is present in food at low levels and accumulates in humans throughout life
because it is not effectively excreted. Cd from smoking or occupational exposure shows …

Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic …

A Kong, Y Zhang, B Ning, K Li, Z Ren, S Dai… - Chemico-Biological …, 2021 - Elsevier
Cadmium (Cd) exposure induced lipid metabolic disorder with changes in lipid composition,
as well as triglyceride (TG) levels. Liver is the main organ maintaining body TG level and …

Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio

YX Pan, Z Luo, MQ Zhuo, CC Wei, GH Chen, YF Song - Aquatic Toxicology, 2018 - Elsevier
The present study was performed to determine the effect of waterborne CdCl 2 exposure
influencing lipid deposition and metabolism, oxidative stress and mitochondrial dysfunction …

Paternal cadmium exposure induces glucolipid metabolic reprogramming in offspring mice via PPAR signaling pathway

L Zeng, J Zhou, Y Zhang, X Wang, Y Li, J Song… - Chemosphere, 2023 - Elsevier
In industrialized societies, the prevalence of metabolic diseases has substantially increased
over the past few decades, yet the underlying causes remain unclear. Cadmium (Cd) is a …