Oncogenic role of fusion-circRNAs derived from cancer-associated chromosomal translocations
Chromosomal translocations encode oncogenic fusion proteins that have been proven to be
causally involved in tumorigenesis. Our understanding of whether such genomic alterations …
causally involved in tumorigenesis. Our understanding of whether such genomic alterations …
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression
W Huang, K Fang, TQ Chen, ZC Zeng, YM Sun… - Journal of hematology & …, 2019 - Springer
Abstract Background Circular RNAs (circRNAs) represent a type of endogenous noncoding
RNAs that are generated by back-splicing events and favor repetitive sequences. Recent …
RNAs that are generated by back-splicing events and favor repetitive sequences. Recent …
Circular RNA F-circSR derived from SLC34A2-ROS1 fusion gene promotes cell migration in non-small cell lung cancer
K Wu, X Liao, Y Gong, J He, JK Zhou, S Tan, W Pu… - Molecular cancer, 2019 - Springer
Cancer-associated chromosomal translocations are reported to generate oncogenic circular
RNA (circRNA), contributing to tumorigenesis. The fusion gene SLC34A2-ROS1 (solute …
RNA (circRNA), contributing to tumorigenesis. The fusion gene SLC34A2-ROS1 (solute …
Genome-wide identification of cancer-specific alternative splicing in circRNA
J Feng, K Chen, X Dong, X Xu, Y Jin, X Zhang… - Molecular Cancer, 2019 - Springer
Circular RNA (circRNA) is a group of RNA families generated by RNA circularization, which
was discovered ubiquitously across different cancers. However, the internal structure of …
was discovered ubiquitously across different cancers. However, the internal structure of …
Mechanisms regulating abnormal circular RNA biogenesis in cancer
Y Huang, Q Zhu - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are circular RNA molecules without a 5′ cap
and a 3′ poly (A) tail structure, which play an important role in tumor development, invasion …
and a 3′ poly (A) tail structure, which play an important role in tumor development, invasion …
Circular RNAs: biogenesis, function and role in human diseases
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
Characterization of distinct circular RNA signatures in solid tumors
C Wang, WR Liu, S Tan, JK Zhou, X Xu, Y Ming… - Molecular Cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) are differentially expressed between normal
and cancerous tissues, contributing to tumor initiation and progression. However …
and cancerous tissues, contributing to tumor initiation and progression. However …
Insights into the role of CircRNAs: biogenesis, characterization, functional, and clinical impact in human malignancies
Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …
CircRNA in cancer: fundamental mechanism and clinical potential
Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …
formed in a circular conformation via non-canonical splicing or back-splicing events …
[HTML][HTML] Circular RNAs in cancer: novel insights into origins, properties, functions and implications
J Li, J Yang, P Zhou, Y Le, C Zhou, S Wang… - American journal of …, 2015 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a large class of RNAs that, unlike linear RNAs, form covalently
closed continuous loops and have recently shown huge capabilities as gene regulators in …
closed continuous loops and have recently shown huge capabilities as gene regulators in …