HOTAIR epigenetically modulates PTEN expression via MicroRNA-29b: a novel mechanism in regulation of liver fibrosis
F Yu, B Chen, P Dong, J Zheng - Molecular Therapy, 2017 - cell.com
Homeobox transcript antisense RNA (HOTAIR), as a long intergenic non-coding RNA
(lincRNA), is upregulated in various cancers and involved in diverse cellular functions …
(lincRNA), is upregulated in various cancers and involved in diverse cellular functions …
[HTML][HTML] Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver
Long non-coding RNAs (lncRNAs) are increasingly recognized as major players in
regulating various biological processes. LncRNA HOX transcript antisense RNA (Hotair) has …
regulating various biological processes. LncRNA HOX transcript antisense RNA (Hotair) has …
LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation
D Cheng, J Deng, B Zhang, X He, Z Meng, G Li, H Ye… - …, 2018 - thelancet.com
Abstract Background MicroRNA-122 (miR-122), a pivotal liver-specific miRNA, is frequently
repressed in hepatocellular carcinoma (HCC) and associated with poor prognosis. Long …
repressed in hepatocellular carcinoma (HCC) and associated with poor prognosis. Long …
Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling
Background & Aims Long non-coding RNA Hotair has been considered as a pro-oncogene
in multiple cancers. Although there is emerging evidence that reveals its biological function …
in multiple cancers. Although there is emerging evidence that reveals its biological function …
Silencing of long non-coding RNA HOTAIR alleviates epithelial–mesenchymal transition in pancreatic cancer via the Wnt/β-catenin signaling pathway
Y Tang, G Song, H Liu, S Yang, X Yu… - Cancer management and …, 2021 - Taylor & Francis
Purpose Pancreatic cancer (PC) is a malignancy with poor prognosis and controversial
treatment options. Long non-coding RNA (lncRNA) is a significant factor in the development …
treatment options. Long non-coding RNA (lncRNA) is a significant factor in the development …
Long non-coding RNA HOTAIR functions as miRNA sponge to promote the epithelial to mesenchymal transition in esophageal cancer
F Xu, J Zhang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Accumulating evidence indicates dysregulated expression of the long non-
coding RNA HOTAIR (lncRNA-HOTAIR) may play a significant role in tumor progression …
coding RNA HOTAIR (lncRNA-HOTAIR) may play a significant role in tumor progression …
[HTML][HTML] LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2
H Li, J An, M Wu, Q Zheng, X Gui, T Li, H Pu, D Lu - Oncotarget, 2015 - ncbi.nlm.nih.gov
Long non-coding RNA HOTAIR predicts negative tumor prognosis and exhibits oncogenic
activity. Herein, we demonstrate HOTAIR promotes human liver cancer stem cell malignant …
activity. Herein, we demonstrate HOTAIR promotes human liver cancer stem cell malignant …
Long non-coding RNA HOTAIR is a marker for hepatocellular carcinoma progression and tumor recurrence
JZ Gao, J Li, JL Du, XL Li - Oncology letters, 2016 - spandidos-publications.com
The present study aimed to investigate the expression level of HOX transcript antisense
RNA (HOTAIR) in hepatocellular carcinoma (HCC) and its association with various …
RNA (HOTAIR) in hepatocellular carcinoma (HCC) and its association with various …
HOTAIR contributes to the growth of liver cancer via targeting miR‑217
LP Wang, JP Wang, XP Wang - Oncology letters, 2018 - spandidos-publications.com
Non‑coding RNAs are important in the progression of liver cancer. The present study aimed
to investigate the effects of long non‑coding RNA HOX transcript antisense RNA (HOTAIR) …
to investigate the effects of long non‑coding RNA HOX transcript antisense RNA (HOTAIR) …
Long noncoding RNA HOTAIR promotes endometrial carcinoma cell proliferation by binding to PTEN via the activating phosphatidylinositol 3-kinase/Akt signaling …
XH Zhang, P Hu, YQ Xie, YJ Kang… - Molecular and cellular …, 2019 - Am Soc Microbiol
Accumulating evidence has demonstrated that long noncoding RNAs (lncRNAs) exert
essential biological functions in modulating the progression of endometrial carcinoma (EC) …
essential biological functions in modulating the progression of endometrial carcinoma (EC) …
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