Bacteria adapt to environmental stimuli by adjusting their transcriptomes in a complex
manner, the full potential of which has yet to be established for any individual bacterial …

The transcriptional regulatory network (TRN) of Bacillus subtilis coordinates cellular
functions of fundamental interest, including metabolism, biofilm formation, and sporulation …

Adaptation of cells to environmental changes requires dynamic interactions between
metabolic and regulatory networks, but studies typically address only one or a few layers of …

Organisms from all domains of life use gene regulation networks to control cell growth,
identity, function, and responses to environmental challenges. Although accurate global …

In its natural habitats, Bacillus subtilis is exposed to changing osmolarity, necessitating
adaptive stress responses. Transcriptomic and proteomic approaches can provide a picture …

The majority of all genes have so far been identified and annotated systematically through in
silico gene finding. Here we report the finding of 3662 strand‐specific transcriptionally active …

Transcription rates are regulated by the interactions between RNA polymerase, sigma factor,
and promoter DNA sequences in bacteria. However, it remains unclear how non-canonical …

INTRODUCTION Bacteria heterogeneously activate gene expression programs in response
to environmental changes, stress, and other stimuli. Such behavior may serve as a bet …

Bacteria respond to diverse growth‐limiting stresses by producing a large set of general
stress proteins. In Bacillus subtilis and related Gram‐positive pathogens, this response is …

Cells use general stress response pathways to activate diverse target genes in response to
a variety of stresses. However, general stress responses coexist with more specific …